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Cobl (NM_172496) Mouse Untagged Clone

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SKU
MC224279
Cobl (untagged) - Mouse cordon-bleu (Cobl), (10ug)
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ORF Plasmid:
Tag Free tGFP DDK
  $1,259.00
7 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Cobl
Synonyms 4732460E13; C530045F18Rik; mKIAA0633
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC224279 representing NM_172496
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGACGCGCCGCGTGCACTGGCGGCCAAGCCCCCCACAGGAAGGAAGATGAAGGCCCGTGCTCCGCCAC
CTCCTGGAAAGCCTGCTGCCCAGAATGTCCACAGCGAACAGAAACTGCCCCATGATGCCACCCTGGGATC
CCAGCAAAGCCTGGTCTACATGAAGGAGGCACTGCAGAACAGCACCTTGGACATCACCGTGGTTCTGCCC
AGTGGACTGGAGAAGCAGAGTGTGGTTAGTGGGAGCCACGCAATGATGGACCTACTGGTTGAACTCTGCC
TTCAGAACCACCTGAATCCTTCTCACCACGTCCTAGAGATCTGGTCTTCTGAGACCCAACAGCCTTTGAG
TTTTAAGCCAAATACGTTGATTGGGTCCTTGAATGTGCATACTGTACTTCTGAAAGAAAAAGTCCCTGAA
GAAAGAGTTAAACCTGGCCTAACCAAGGCTCCTGAGAAATCTGTACGACTGGTAGTGAACTACCTGAGAA
CGCAGAAGGCTGTCGTGCGGGTGAGCCCTGAGGTGCCACTACAGAATATTCTGCCAGTCATCTGTGCGAA
GTGTGAGGTCAACCCAGAACACGTGATTCTGCTCAGAGACAATGTTGCCGGGGAGGAGCTGGAGCTGTCC
AAGTCCCTGAATGAACTAGGGATCAAGGAGCTGTATGCGTGGGACAACAGAAGAGAAATGTTTAGAAAAT
CATCACTTGGCAATGATGAGACAGACAAAGAGAAGAAAAAGTTTCTGGGATTTTTCAAAGCTAATAAAAG
GAGCAACAGTAAGGCTGAGCATCTTGGGCTGTCAGGTGCAGATAGTGATGAGGACCCGGCGAAGTCAGCA
TCTGGAGGGGACTTGAACGGCTGCGTAACAACACCCAACTCACCATCCTTGCATTCTCGGTCCCTAACAC
TGGGTCCCTCCCTCTCCCTGGGCAACATCTCTGGAGTGTCTATGAAGTCAGACATGAAGAAGCGCAGAGC
CCCTCCTCCTCCAAGTCCCAAGCTGCTGGGTCAAGACAAGGTATCAGAAAAGGCCTCCCTCAGCTCACAG
GCTGATCTCCAGAAGAAGAAGAGGCGGGCGCCAGCTCCTCCTCCACCACAGCAGCCACCACCAAGTCCTG
TGGTCCCCAACCGCAAGGAAGATAAGGAAGAGAACAGGAAGAGCACAGTGGGTGTTGGACGTCAGGTGCC
ACAAAAGCCTCCCAGAGGCACAGCTCGGGGCCCACCCCAGTTAGTGCTCCCCCCGCCCCCACCCTACCCT
CCTCCTGACACAGATGTGACAGAGCCTGTCACCTTTCCTGGGGAAGGCGCTGGTTCCGAGACCTCAGAGC
TGAGACCCAAACTGAGTCTGCCTCTGGGGCCTGGCAGCCACTGCAGCATGGGTGGAGTCTCTCAGGTGCC
AGCGGAGAGTGAGGAGACAGCATCTGAGGACACAACCGAGGACTCGGGGGTCATGAGCTCTCCCTCAGAT
GCCATCTCCCTGGACTCACAACAAGACAGCATGAGATCCAAGGACAAATGGTCCACAGACCAGGAAGACG
GCAGTGACCAGGACCTGGCTGGAACTCCAGAACTGGGTCCCCAAAAGAGCCCATCATGGGGGAAAAGTGG
TTCAGGAAGCTCAATTCTAAGGACTGAGAAAGCCACCATGCCTACCAATGATGATGAAGACCTATTCATC
ACTGGCCACTTACATCAGACCCTGGCAGAACTTGATGAAGACCTGGAAGGAATGGAAGAAAATTATGAAA
CAGATACTAGCTCTCTAACCAACTCTGTCAATGGTGTATCCAACCACAGTCTGCAAGAAGCCATAATCCC
TGATAGTGGCGTGGATGACATCCCAGTCACTTTTATCGGGGAAGTTTCTGATGAGCCTTTTGACTCAGGG
CTGTTCTCCAGTAGATGTAACAATGCCACTACTTTTAACACGGGGAGCATTGCTAGCCAAAGATCTCATC
TGTCCCCATCTCAGACTGAGCATAGCCAGCCATTCGTAAGGACAAGTAGAAAAGAGCCTGATCCCTCCCC
TCCTTCCCAAGATAACAGGAAGAGAAATCAGCCAACCTTAGCCAACACATCTGAAAATGAGAATCCAGTT
GAAACAGACCCCACAGTTACATCACTTGTTTCAAAGCTTTTAATAGATGACCCAAAAGCAAAGGATAAAG
GCAAAGTGCATGGTTCTAGTCACAGTGAGAAGACACAGGCAGGTCATGGAATAAACTCACTGCGAGTGAA
TCCAAGAGATGGTAAGGATGAGAGCTCCAATTCAGCACCCCCACCATGGTCTCATCATGGCCAGGCCTTA
GGGGGAAGCTATGGACTCAAGTATGGCCTCACGACATATAAAATTGTTCCTCCCAAATCAGAGATGAGGT
GTTATGACAGGGATGTGTCCCTCTCCACTGGTGCCATTAAGATTGATGAACTAGGGAATCTGGTGAGTCC
TCACATGAACGGAAGCAGGACCATATCCCCACCATCAGCTGTTGTCGAAACAGACACTCCACCTATTGGA
AAAGTCAAAGAGTTCTGGAGGCGCAACTCAATGGAAAAGTACCTTAATGGGCCGGCTGAGTGCACTATCA
AAAGGGCCCCCTCCACCACTATCACTGCCACACCAGAAAAACCACAGCAAGATAATGGGATGAAGGCAGC
CTTCACAGTGACCACTCCCCAGCAGCAGCCTGCCTCACAGGAATATGGGGCACACCTGGAGGAAGAGAGA
AGCCGGCCACAGTCAGCAGTCTCTTGTTCTGTGAAAGTGCCAGCATCTAATCCCACAGACATCACATTCC
TCAAGCCTCAAAGAAGAACATCCAGCCAGTATGTGGCCTCTGCTATTGCCAAGAAGATGGGGCCTCCAAA
AGTCCATGCTGATGTGGTGAGACCACATAAGGCAACCACTGAACAGTGTCATGAAGAAGCAAAGCTGGCT
AGATCTCCTCCCACCAGGAAAGATGATGCAGCTCCCAACCTACACTCAGAGGCAAGGCAGCATGAACATG
GGACAAACCAGAGCTCTGTCTGCCTTCCCAGCAACCCTGGTGTGCAATTGCCAGCAGGAGGCCATCCCAA
AGTAGAGGTCAACAGCACATATGGGAAGTCATCGACTCAAGACTATCCTGCTGCTGTCCACAGAAACTCC
TATTTCCTCCCAGGCAGATCTTCCCATAGGGATCGTGTTTCTGTGGGACAGAGCTGTGGTTTCAATGAAA
AGCAAACTACAAGTAACCAAAAGGCAAATTCAACATCTAACTTCTCGCAGGCACTGGACAAGGCGCATCC
ACCCCCTCTGCTCTTGGCAGAGGCCCGTGACTCTGGGAGGATACTGATGAATGGCTCTGCACGAACCCCA
GGAAATTGTGAGCCCCCCCACTCTCCAAAAGAATCCACCCTGACTAGCTATATTATCTTACAGACAGAGG
AAAAGCCCAGTTCGTTATCTACAGATGGTCAAGACGCAGATGATACTCTACCGTCCAGCATTTTTGGGCC
AAAGAAAAAGTTCAAGCCTGTCATTCAAAGGCCACTCCCAAAAGATGTATCCCTGCACAGTGCCCTGATG
GAAGCTATCCACTCATCAGGAGGGAGAGAAAAGCTCCGGAAGACTGCAGAACAGACGTCAGAAGGAAGGC
CAAAGAAACCATCCTACGTGGAGGCAGAGAGTGAGCGATCTGCCCTTCTGGCAGCCATTCGGGGTCACAG
TGGGACTCTCAGCCTCAGGAAGGTGTCATCCCTTGCCTCTGAGGAGCTCCAGAGCTTCCGCAATGCTGCA
CTCGGGGCTCCAGGTTTGGATAAACCTCAGCAAGAAGACCTTGGCCTTCCACCCCCACCTGCCCTGCCAC
CACCACCCGCTCCAGCCCCCCAGGCTCCTTCAGCCTCCGTAACAGTTTCTAGGTTCAGCACCGGCACCCC
CAGCAACTCAGTGAATGCTAGACAAGCCTTGATGGATGCCATCCGCTCGGGCACAGGAGCTGCAAGACTA
AGAAAGGTTCCCTTGCTCGTGTGA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_172496
Insert Size 4014 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_172496.3, NP_766084.3
RefSeq Size 5633 bp
RefSeq ORF 4014 bp
Locus ID 12808
UniProt ID Q5NBX1
Cytogenetics 11 7.3 cM
Summary Plays an important role in the reorganization of the actin cytoskeleton. Binds to and sequesters actin monomers (G actin). Nucleates actin polymerization by assembling three actin monomers in cross-filament orientation and thereby promotes growth of actin filaments at the barbed end. Can also mediate actin depolymerization at barbed ends and severing of actin filaments. Promotes formation of cell ruffles. Regulates neuron morphogenesis and increases branching of axons and dendrites. Regulates dendrite branching in Purkinje cells.UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
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Documents
Resources
"NM_172496" in other vectors (4)
SKU Description Size Price
MG217651 Cobl (tGFP-tagged) - Mouse cordon-bleu (Cobl), (10ug) 10 ug
$1,344.00
MR217651 Cobl (Myc-DDK-tagged) - Mouse cordon-bleu (Cobl) 10 ug
$589.00 $1,144.00
MR217651L3 Lenti ORF clone of Cobl (Myc-DDK-tagged) - Mouse cordon-bleu (Cobl) 10 ug
$1,444.00
MR217651L4 Lenti ORF clone of Cobl (mGFP-tagged) - Mouse cordon-bleu (Cobl) 10 ug
$1,444.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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