Tbcd (NM_029878) Mouse Untagged Clone
$1,042.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Tbcd |
| Synonyms | 2310057L06Rik; A030005L14Rik; mKIAA0988 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_029878 |
| Insert Size | 3591 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_029878.3, NP_084154.1 |
| RefSeq Size | 3912 bp |
| RefSeq ORF | 3591 bp |
| Locus ID | 108903 |
| UniProt ID | Q8BYA0 |
| Cytogenetics | 11 E2 |
| Summary | Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane. Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis. Involved in neuron morphogenesis.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_029878" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG211787 | Tbcd (tGFP-tagged) - Mouse tubulin-specific chaperone d (Tbcd) | 10 ug |
$1,242.00
|
|
| MR211787 | Tbcd (Myc-DDK-tagged) - Mouse tubulin-specific chaperone d (Tbcd) | 10 ug |
$589.00
$1,042.00
|
|
| MR211787L3 | Lenti ORF clone of Tbcd (Myc-DDK-tagged) - Mouse tubulin-specific chaperone d (Tbcd) | 10 ug |
$1,342.00
|
|
| MR211787L4 | Lenti ORF clone of Tbcd (mGFP-tagged) - Mouse tubulin-specific chaperone d (Tbcd) | 10 ug |
$1,342.00
|
|
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