Kdm2a (NM_001001984) Mouse Untagged Clone
$1,113.00
6 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Kdm2a |
| Synonyms | 5530401A10Rik; 100043628; AA589516; AW536790; Cxxc8; Fbl7; Fbl11; Fbxl11; Gm4560; Jhdm1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_001001984 |
| Insert Size | 3486 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001001984.2, NP_001001984.2 |
| RefSeq Size | 7268 bp |
| RefSeq ORF | 3486 bp |
| Locus ID | 225876 |
| UniProt ID | P59997 |
| Cytogenetics | 19 A |
| Summary | Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis (By similarity). Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
"NM_001001984" in other vectors (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MR210889 | Kdm2a (Myc-DDK-tagged) - Mouse lysine (K)-specific demethylase 2A (Kdm2a) | 10 ug |
$589.00
$765.00
|
|
| MR210889L3 | Lenti ORF clone of Kdm2a (Myc-DDK-tagged) - Mouse lysine (K)-specific demethylase 2A (Kdm2a) | 10 ug |
$1,065.00
|
|
| MR210889L4 | Lenti ORF clone of Kdm2a (mGFP-tagged) - Mouse lysine (K)-specific demethylase 2A (Kdm2a) | 10 ug |
$1,065.00
|
|
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.