Kank2 (NM_145611) Mouse Untagged Clone
$850.00
5 Weeks*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Kank2 |
| Synonyms | AI504612; Ankrd25; BC010245 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_145611 |
| Insert Size | 2532 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_145611.4, NP_663586.3 |
| RefSeq Size | 4853 bp |
| RefSeq ORF | 2532 bp |
| Locus ID | 235041 |
| UniProt ID | Q8BX02 |
| Cytogenetics | 9 A3 |
| Summary | Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (By similarity). Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (By similarity). Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (By similarity). Involved in the negative control of vitamin D receptor signaling pathway (By similarity). Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PubMed:25961457). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PubMed:25961457). Through the Rho signaling pathway may also regulate cell proliferation (PubMed:16024821).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_145611" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG216907 | Kank2 (tGFP-tagged) - Mouse KN motif and ankyrin repeat domains 2 (Kank2), (10ug) | 10 ug |
$972.00
|
|
| MR216907 | Kank2 (Myc-DDK-tagged) - Mouse KN motif and ankyrin repeat domains 2 (Kank2) | 10 ug |
$589.00
$772.00
|
|
| MR216907L3 | Lenti ORF clone of Kank2 (Myc-DDK-tagged) - Mouse KN motif and ankyrin repeat domains 2 (Kank2) | 10 ug |
$1,072.00
|
|
| MR216907L4 | Lenti ORF clone of Kank2 (mGFP-tagged) - Mouse KN motif and ankyrin repeat domains 2 (Kank2) | 10 ug |
$1,072.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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