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Itgb8 (NM_177290) Mouse Untagged Clone

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SKU
MC221469
Itgb8 (untagged) - Mouse integrin beta 8 (Itgb8), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $1,125.00
5 Weeks*
Bulk Requests & Clone Modifications

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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Itgb8
Synonyms 4832412O06Rik
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC221469 representing NM_177290
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGTGCGGCTCGGCCCTGGCTTTTCTGACTGCTGCACTGCTCTCTCTGCACAACTGCCAGCGAGGTCCAG
CCTTGGTTCTTGGGGCAGCCTGGGTATTTTCACTTGTTCTCGGACTGGGCCAAAGTGAACACAATAGATG
TGGCTCTGCAAATGTGGTCTCCTGTGCCAGGTGCCTCCAGCTGGGTCCGGAATGCGGATGGTGTGTTCAA
GAGGATTTTGTTTCAGGTGGATCAGGAAGTGAACGTTGTGATACTGTTTCCAGTTTGATAAGCAAAGGCT
GTCCAGTTGATTCAATAGAATACCTGTCTGTGCATGTTGTAACGTCAAGTGAGAATGAAATCAATACCCA
GGTGACACCGGGAGAAGTCTCAGTCCAACTGCATCCAGGAGCTGAAGCTAATTTTATGTTAAAAGTCCGT
CCTCTGAAGAAATACCCCGTGGATCTTTATTATCTGGTTGATGTGTCAGCATCAATGCACAATAATATAG
AAAAATTGAATTCCGTTGGAAATGATTTATCTAAAAAAATGGCCCTTTATTCCCGTGACTTCCGTCTTGG
TTTTGGCTCATATGTGGATAAAACTGTCTCGCCATACATTAGTATCCACCCGGAAAGGATCCACAATCAG
TGCAGTGACTACAATTTAGACTGTATGCCTCCCCATGGATACATTCATGTGCTGTCTCTGACAGAAAACA
TCACTGAGTTTGAAAAAGCAGTCCACAGACAAAAGATCTCTGGAAACATAGACACCCCTGAAGGAGGTTT
TGATGCCATGCTTCAGGCTGCCGTCTGTGAGAGTCATATTGGATGGCGAAAAGAAGCTAAAAGATTGCTG
CTGGTGATGACAGACCAGACATCACATCTTGCTCTTGACAGCAAATTGGCAGGCATAGTGGTGCCGAATG
ACGGAAACTGCCATCTCAAAAACAATGTCTACGTCAAATCGACAACCATGGAACATCCGTCATTAGGCCA
ACTTTCTGAAAAGTTAATAGACAACAACATAAATGTCATTTTTGCAGTTCAAGGAAAGCAGTTTCATTGG
TACAAGGACCTTCTGCCCCTTTTGCCTGGTGCCATTGCTGGTGAAATAGAATCCAAAGCTGCAAATCTCA
ACAATTTAGTAGTAGAAGCCTACAAGAAGATTATCTCAGAAGTAAAAGTGCAGCTGGAAAACCAGGTACA
CGGTGTCCATTTTAACATCACTGCCATCTGTCCAGATGGGGCCAGAAAGCCAGGCATAAGTGGGTGTGGA
AACGTGACAAGCAATGACGAAGTTCTTTTCAATGTAACTGTTGTGATGAAAACATGTGATATCATGGGAG
GAAAAAACTATGCAATAATCAAGCCTATTGGTTTCAATGAAACCACTAAAGTCCACATACACAGAAGCTG
CAGTTGCCAGTGTGAGAACCACAGAGGACTCAAAGGACAGTGTGCGGAAGCTGCCCCAGACCCCAAGTGT
CCACAGTGTGATGACAGCAGATGTCATTTTGATGAAGACCAGTTTCCTTCTGAAACTTGCAAGCCACAGG
AGGATCAACCTGTCTGCAGTGGCCGAGGTGTTTGCATCTGTGGGAAATGTTTATGTCACAAAACCAAGCT
AGGAAGAGTGTATGGCCAGTACTGTGAGAAGGATGACTTCTCCTGTCCCTATCTCCATGGGGATGTGTGT
GCTGGGCATGGGGAGTGTGAAGGTGGCAGATGCCAGTGCTTTAGTGGCTGGGAAGGAGATCGGTGTCAGT
GCCCATCAGCCTCAGCACAGCACTGTGTCAACTCCAAGGGCCAAGTTTGCAGCGGGAGAGGCACCTGCGT
GTGTGGCAGGTGTGAGTGTACTGATCCCAGAAGCATTGGCCGTCTCTGTGAGCACTGCCCAACCTGCCAT
CTCTCCTGCAGTGAAAACTGGAATTGTCTGCAGTGCCTTCACCCTCACAATCTGTCTCAGGCTGCCCTTG
ATCAGTGTAAATCCTCCTGTGCTGTCATGGAACAGCATCGCATGGACCAAACATCAGAATGTTTATCTGG
CCCAAGCTATCTGCGAATATTTTTCATCATATTCATAGTCACATTCTTGATCGGGTTGCTTAAAGTTCTT
ATCATTAGACAAGTGATACTACAATGGAATAATAATAAAATAAAGTCCTCATCAGATTATAGAATGTCTG
CTTCTAAAAAGGATAAACTGATTCTGCAAAGTGTTTGCACGAGAGCTGTAACCTACCGACGAGAAAAGCC
TGAGGAAATAAAAATGGATATCAGCAAACTAAATGCTCAGGAGGCCTTCAGGTGCAACTTCTAA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_177290
Insert Size 2304 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_177290.3, NP_796264.2
RefSeq Size 3096 bp
RefSeq ORF 2304 bp
Locus ID 320910
UniProt ID Q0VBD0
Cytogenetics 12 F2
Summary Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (PubMed:25127859). Required during vasculogenesis (PubMed:12050137, PubMed:16251442).UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_177290" in other vectors (4)
SKU Description Size Price
MG227668 Itgb8 (tGFP-tagged) - Mouse integrin beta 8 (Itgb8), (10ug) 10 ug
$1,253.00
MR227668 Itgb8 (Myc-DDK-tagged) - Mouse integrin beta 8 (Itgb8) 10 ug
$1,053.00
MR227668L3 Lenti ORF clone of Itgb8 (Myc-DDK-tagged) - Mouse integrin beta 8 (Itgb8) 10 ug
$1,353.00
MR227668L4 Lenti ORF clone of Itgb8 (mGFP-tagged) - Mouse integrin beta 8 (Itgb8) 10 ug
$1,353.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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