Srrm4 (NM_026886) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Srrm4 |
| Synonyms | 1500001A10Rik; B230202K19Rik; bv; mKIAA1853; nSR100 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_026886 |
| Insert Size | 1827 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_026886.3, NP_081162.1 |
| RefSeq Size | 7476 bp |
| RefSeq ORF | 1827 bp |
| Locus ID | 68955 |
| UniProt ID | Q8BKA3 |
| Cytogenetics | 5 F |
| Summary | Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural cell differentiation. Required to promote the inclusion of neural-specific exon 10 in nPTB/PTBP2, leading to increased expression of neural-specific nPTB/PTBP2. Also promotes the inclusion of exon 16 in DAAM1 in neuron extracts (PubMed:19737518). Promotes alternative splicing of REST transcripts to produce REST isoform 2 (REST4) with greatly reduced repressive activity, thereby activating expression of REST targets in neural cells (PubMed:21884984). Plays an important role during embryonic development as well as in the proper functioning of the adult nervous system. Regulates alternative splicing events in genes with important neuronal functions (PubMed:25838543).UniProtKB/Swiss-Prot Function |
Reviews
Documents
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| FAQs |
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Resources
"NM_026886" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG209379 | Srrm4 (tGFP-tagged) - Mouse RIKEN cDNA 1500001A10 gene (1500001A10Rik) | 10 ug |
$489.00
$767.00
|
|
| MR209379 | Srrm4 (Myc-DDK-tagged) - Mouse serine/arginine repetitive matrix 4 (Srrm4) | 10 ug |
$289.00
$567.00
|
|
| MR209379L3 | Lenti ORF clone of Srrm4 (Myc-DDK-tagged) - Mouse serine/arginine repetitive matrix 4 (Srrm4) | 10 ug |
$867.00
|
|
| MR209379L4 | Lenti ORF clone of Srrm4 (mGFP-tagged) - Mouse serine/arginine repetitive matrix 4 (Srrm4) | 10 ug |
$867.00
|
|
Citations
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