Nr2c2 (NM_011630) Mouse Untagged Clone

SKU MC219522

Nr2c2 (untagged) - Mouse nuclear receptor subfamily 2, group C, member 2 (Nr2c2), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Nr2c2
• Synonyms: mKIAA4145; TAK1; Tr4
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC219522 representing NM_011630; Red=Cloning site Blue=ORF Orange=Stop codon; ; TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC; GCCGCGATCGCC; ; ATGACCAGCCCCTCCCCGCGCATCCAGATAATTTCCACCGACTCTGCGGTAGCCTCACCTCAGCGCATTC; AGATTGTAACAGACCAGCAGACAGGACAAAAGATCCAGATAGTCACCGCAGTGGATGCCTCTGGATCCTC; TAAACAGCAGTTCATCCTAACCAGCCCAGATGGAGCTGGAACTGGGAAGGTGATCCTGGCTTCTCCGGAA; ACATCCAGTGCCAAGCAGCTCATATTCACCACCTCGGACAACCTTGTCCCTGGCAGGATCCAGATCGTCA; CGGATTCTGCTTCTGTGGAGCGTTTGCTGGGGAAGGCAGACGTCCAGCGGCCCCAGGTGGTGGAGTACTG; TGTGGTCTGTGGCGACAAAGCCTCTGGCCGGCACTATGGGGCTGTCAGTTGTGAAGGTTGCAAAGGTTTC; TTCAAAAGGAGCGTGAGGAAGAATCTGACCTACAGCTGTCGGAGCAGCCAAGACTGCATCATCAACAAGC; ACCACCGTAACCGCTGCCAGTTCTGCCGGCTGAAGAAGTGCCTGGAGATGGGCATGAAAATGGAGTCTGT; ACAGAGTGAACGGAAGCCCTTTGATGTGCAACGGGAGAAACCAAGCAATTGTGCTGCTTCCACTGAGAAG; ATCTATATCCGGAAAGACCTGAGAAGTCCTCTGATAGCCACTCCCACATTTGTGGCAGACAAAGATGGAG; CAAGACAAACAGGTCTTCTTGATCCAGGGATGCTTGTGAACATCCAACAGCCTTTGATACGTGAGGATGG; TACAGTTCTCCTGGCCGCGGATTCCAAGGCTGAAACAAGCCAAGGAGCTCTAGGTACACTGGCAAATGTA; GTGACCTCTTTGGCCAACCTGAGTGAATCTTTGAACAACGGTGATGCTTCAGAAATGCAGCCAGAGGACC; AGTCTGCAAGTGAGATTACTCGGGCATTTGACACCTTAGCGAAAGCACTTAATACCACAGATAGTGCTTC; ACCTCCAAGCCTGGCAGATGGGATAGATGCTAGTGGAGGAGGGAGTATCCATGTCATCAGCAGAGATCAG; TCAACACCCATCATTGAAGTTGAAGGCCCTCTCCTTTCAGACACACATGTCACATTCAAGCTTACAATGC; CCAGTCCTATGCCAGAGTACCTCAATGTACATTACATCTGTGAGTCTGCATCCCGCCTGCTTTTCCTCTC; CATGCACTGGGCAAGGTCAATCCCAGCCTTCCAGGCACTTGGACAGGACTGTAATACCAGCCTGGTGAGG; GCCTGCTGGAATGAGCTCTTCACTCTTGGCCTGGCCCAGTGTGCCCAGGTCATGAGTCTCTCCACCATCC; TGGCAGCCATTGTCAACCACCTACAGAACAGCATCCAGGAAGATAAGCTTTCTGGTGACCGGATAAAGCA; AGTGATGGAGCACATCTGGAAGCTGCAGGAGTTCTGTAACAGCATGGCGAAACTGGATATAGACGGCTAT; GAGTACGCATACCTTAAAGCTATAGTTCTCTTTAGTCCCGATCATCCAGGTTTGACAGGCACAAGCCAGA; TTGAGAAATTTCAGGAGAAGGCACAGATGGAATTACAGGACTATGTGCAGAAAACCTACTCTGAAGATAC; TTACAGATTGGCCAGGATTCTTGTCCGCCTACCAGCACTCAGGCTCATGAGCTCCAACATAACAGAAGAA; CTTTTTTTTACTGGTCTCATTGGCAATGTTTCAATAGACAGCATAATTCCTTACATCCTCAAGATGGAGA; CAGCAGAATATAATGGCCAGATCACTGGAGCCAGTCTATAG; ; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT; ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011630
• Insert Size: 1791 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_011630.3, NP_035760.1
• RefSeq Size: 7637 bp
• RefSeq ORF: 1791 bp
• Locus ID: 22026
• UniProt ID: P49117
• Cytogenetics: 6 D1
• Summary: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Activates transcriptional activity of LHCG and is antagonist of PPARA-mediated transactivation (By similarity). Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior.[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (2) differs in the 5' UTR and coding region, compared to variant 1. These differences cause translation initiation at a downstream AUG and results in an isoform (2) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.