Nr2c1 (NM_011629) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Nr2c1 |
| Synonyms | 80.3; 4831444H07Rik; Eenr; TR2; Tr2-11 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_011629 |
| Insert Size | 1773 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_011629.3, NP_035759.3 |
| RefSeq Size | 3827 bp |
| RefSeq ORF | 1773 bp |
| Locus ID | 22025 |
| UniProt ID | Q505F1 |
| Cytogenetics | 10 48.81 cM |
| Summary | Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes including ESR1 and RARB. Together with NR2C2, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences (By similarity). Also activator of OCT4 gene expression. Plays a fundamental role in early embryogenesis and regulates embryonic stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_011629" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG209201 | Nr2c1 (tGFP-tagged) - Mouse nuclear receptor subfamily 2, group C, member 1 (Nr2c1) | 10 ug |
$750.00
|
|
| MR209201 | Nr2c1 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 2, group C, member 1 (Nr2c1) | 10 ug |
$289.00
$550.00
|
|
| MR209201L3 | Lenti ORF clone of Nr2c1 (Myc-DDK-tagged) - Mouse nuclear receptor subfamily 2, group C, member 1 (Nr2c1) | 10 ug |
$850.00
|
|
| MR209201L4 | Lenti ORF clone of Nr2c1 (mGFP-tagged) - Mouse nuclear receptor subfamily 2, group C, member 1 (Nr2c1) | 10 ug |
$850.00
|
|
Citations
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