Mmp14 (NM_008608) Mouse Untagged Clone
SKU
MC219253
Mmp14 (untagged) - Mouse matrix metallopeptidase 14 (membrane-inserted) (Mmp14), (10ug)
$543.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Mmp14 |
| Synonyms | AI325305; MMP-X1; MT-MMP-1; MT1-MM; MT1-MMP; sa; sabe |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_008608 |
| Insert Size | 1749 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_008608.4, NP_032634.3 |
| RefSeq Size | 3801 bp |
| RefSeq ORF | 1749 bp |
| Locus ID | 17387 |
| UniProt ID | P53690 |
| Cytogenetics | 14 27.79 cM |
| Summary | This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprotein undergoes proteolytic processing to generate a mature, zinc-dependent endopeptidase enzyme. Mice lacking the encoded protein exhibit craniofacial dysmorphism, arthritis, osteopenia, dwarfism, and fibrosis of soft tissues. provided by RefSeq, Feb 2016 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_008608" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG209110 | Mmp14 (tGFP-tagged) - Mouse matrix metallopeptidase 14 (membrane-inserted) (Mmp14) | 10 ug |
$489.00
$742.00
|
|
| MR209110 | Mmp14 (Myc-DDK-tagged) - Mouse matrix metallopeptidase 14 (membrane-inserted) (Mmp14) | 10 ug |
$289.00
$542.00
|
|
| MR209110L3 | Lenti ORF clone of Mmp14 (Myc-DDK-tagged) - Mouse matrix metallopeptidase 14 (membrane-inserted) (Mmp14) | 10 ug |
$842.00
|
|
| MR209110L4 | Lenti ORF clone of Mmp14 (mGFP-tagged) - Mouse matrix metallopeptidase 14 (membrane-inserted) (Mmp14) | 10 ug |
$842.00
|
|
Citations
Paradoxical Changes: EMMPRIN Tissue and Plasma Levels in Marfan Syndrome-Related Thoracic Aortic Aneurysms
Alexander, Anderson, Agala et al
J Clin Med (2024) 13 (6) DOI: 10.3390/jcm13061548
Alexander, Anderson, Agala et al
J Clin Med (2024) 13 (6) DOI: 10.3390/jcm13061548
Cited by 3
AI Summary: OriGene’s MT1-MMP overexpression vector (MC219253) was used to manipulate MT1-MMP levels in aortic fibroblasts, enabling the study of its role in EMMPRIN secretion in Marfan syndrome-related thoracic aortic aneurysms.
Snippet: g jetPRIME transfection reagent (114-15, Polypolus-transfection Illkirch-Graffenstaden, France) according to the DNA transfection protocol with either 10 µg MT1-MMP over expression vector (MC219253, OriGene, Rockville, MD, USA) or the transfection reagent alone. Following the 18 h incubation, the culture media was replaced with fresh, serum-free media for 48 hours. EMMPRIN levels were quantified
Showing 1-1 of 1 papers.
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