Rgma (BC023870) Mouse Untagged Clone

SKU
MC218652
Rgma (untagged) - Mouse RGM domain family, member A (cDNA clone MGC:38550 IMAGE:5353958), (10ug)
  $503.00
3 Weeks*
Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Rgma
Synonyms C230063O06, MGC38550, MGC69915
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC023870
Red=Cloning site Blue=ORF Green=Tags(s)

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGTATGGGGAGAGGGGCAGGACGTTCAGCCCTGGGATTGTGGCCGACCCTCGCCTTCCTTCTCTGCA
GCTTCCCCGCAGCCATCTCCCCCTGCAAAATCCTCAAGTGCAACTCTGAGTTCTGGAGCGCCACGTCATC
AGGCAGCCACGCCCCTGCCTCCGACGACGTGCCGGAGTTCTGTGCAGCCCTGCGCACCTACGCCCTGTGC
ACTCGGCGGACAGCCCGCACCTGCCGGGGCGACCTGGCTTACCACTCGGCTGTCCATGGCATAGAGGACC
TTATGAGCCAGCACAACTGCTCCAAGGACGGCCCCACCTCACAGCCGCGAGTGCGCACGCTCCCGCCAGC
TGGGGACAGCCAGGAGCGCTCGGATAGCCCCGAGATCTGCCACTATGAGAAGAGTTTCCACAAGCACTCA
GCTGCCCCCAACTACACTCACTGCGGCCTCTTTGGGGACCCACACCTCAGGACTTTCACAGACCACTTCC
AGACATGCAAGGTGCAAGGCGCCTGGCCTCTCATCGACAATAATTACCTGAACGTGCAAGTCACCAATAC
ACCTGTGCTGCCGGGCTCCGCAGCTACCGCCACCAGCAAGCTCACCATCATCTTCAAGAACTTCCAAGAG
TGTGTGGACCAGAAAGTCTACCAAGCTGAAATGGACGAACTTCCGTCTGCCTTTGCGGACGGCTCCAAAA
ATGGGGGAGATAAACACGGGGCCAACAGCCTGAAGATCACAGAGAAGGTGTCGGGCCAGCACGTGGAGAT
CCAGGCCAAGTACATCGGCACCACCATCGTGGTGCGACAGGTGGGCCGCTACCTGACCTTTGCCGTCCGG
ATGCCCGAGGAGGTAGTCAACGCCGTGGAGGACCGTGACAGCCAAGGCCTCTACCTCTGCCTGCGGGGCT
GCCCGCTCAACCAGCAGATCGACTTCCAGGCTTTCCGTGCCAACGCTGAAAGCCCTCGCAGGCCAGCAGC
CGCCAGTCCCTCTCCCGTGGTCCCCGAGACATTCCCCTATGAGACAGCCGTGGCCAAGTGCAAAGAGAAG
CTGCCCGTAGAAGACCTGTACTACCAGGCCTGTGTCTTCGACCTCCTCACGACTGGTGATGTGAACTTCA
CGCTGGCTGCCTACTATGCTTTGGAGGATGGCAAGATGCTCCACTCCAACAAGGACAAGCTGCATCTGTT
TGAAAGGACTCGGGAGCTGCCAGGAGCCGTGGCCGCCGCCGCCGCTGCCACCACATTCCCCTTGGCCCCC
CAGATTCTCCTTGGCACCATCCCACTTCTGGTCCTCCTGCCTGTGTTGTGGTAG


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAG
GTTTAA
Restriction Sites SgfI-MluI |
ACCN BC023870
Insert Size 1314 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC023870, AAH23870
RefSeq Size 3407 bp
RefSeq ORF 1313 bp
Locus ID 244058
Cytogenetics 7 D1
Summary Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA-ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG-PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inactivation by influencing HRAS-PTK2/FAK1-AKT1 pathway. It also functions as a bone morphogenetic protein (BMP) coreceptor that may signal through SMAD1, SMAD5, and SMAD8.UniProtKB/Swiss-Prot Function
Reviews
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
"BC023870" in other vectors (4)
SKU Description Size Price
MG206975 Rgma (tGFP-tagged) - Mouse RGM domain family, member A (cDNA clone MGC:38550 IMAGE:5353958) 10 ug
$489.00 $657.00
MR206975 Rgma (Myc-DDK-tagged) - Mouse RGM domain family, member A (cDNA clone MGC:38550 IMAGE:5353958) 10 ug
$289.00 $457.00
MR206975L3 Lenti ORF clone of Rgma (Myc-DDK-tagged) - Mouse RGM domain family, member A (cDNA clone MGC:38550 IMAGE:5353958) 10 ug
$757.00
MR206975L4 Lenti ORF clone of Rgma (mGFP-tagged) - Mouse RGM domain family, member A (cDNA clone MGC:38550 IMAGE:5353958) 10 ug
$757.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products