Sox10 (NM_011437) Mouse Untagged Clone

SKU MC218241

Sox10 (untagged) - Mouse SRY-box containing gene 10 (Sox10), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Sox10
• Synonyms: Dom; gt; Sox21
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >MC218241 representing NM_011437; Red=Cloning site Blue=ORF Orange=Stop codon; ; TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC; GCCGCGATCGCC; ; ATGGCCGAGGAACAAGACCTATCAGAGGTGGAGCTGAGCCCTGTGGGCTCGGAGGAACCCCGCTGCCTGT; CCCCAGGCAGCGCGCCGTCGCTGGGACCCGACGGCGGCGGCGGTGGCTCGGGCTTGCGAGCCAGCCCGGG; GCCCGGTGAACTGGGCAAGGTCAAGAAGGAACAGCAGGACGGCGAGGCGGACGATGACAAGTTCCCCGTG; TGCATCCGCGAGGCGGTCAGCCAGGTGCTCAGCGGCTACGACTGGACGCTGGTGCCCATGCCCGTGCGCG; TCAACGGTGCCAGCAAGAGCAAGCCGCACGTCAAGAGGCCCATGAACGCCTTCATGGTGTGGGCACAGGC; GGCACGCAGAAAGCTAGCCGACCAGTACCCTCACCTCCACAATGCTGAGCTCAGCAAGACACTAGGCAAG; CTCTGGAGGTTGCTGAACGAAAGTGACAAGCGCCCCTTCATTGAGGAGGCTGAGAGGCTCCGGATGCAGC; ACAAAAAGGACCATCCGGACTACAAGTACCAACCTCGGCGGCGGAAGAACGGGAAGGCAGCCCAGGGGGA; GGCAGAATGCCCAGGCGGGGAAGCCGAGCAAGGAGGGGCTGCTGCTATTCAGGCTCACTACAAGAGTGCC; CACCTGGACCACCGGCACCCAGAAGAAGGCTCCCCCATGTCAGATGGGAACCCAGAGCACCCCTCAGGCC; AGAGCCATGGCCCCCCAACCCCTCCAACCACCCCAAAGACAGAGCTGCAGTCCGGCAAGGCAGACCCCAA; AAGGGATGGGCGCTCCTTGGGGGAGGGCGGGAAGCCCCACATCGACTTCGGCAACGTGGACATCGGGGAG; ATCAGCCACGAGGTAATGTCCAACATGGAAACCTTTGATGTGACTGAGCTGGACCAATACCTGCCACCCA; ACGGGCACCCAGGCCATGTGGGTAGCTACTCGGCAGCTGGCTACGGGCTGGGCAGTGCCCTGGCTGTGGC; CAGTGGACACTCTGCCTGGATCTCCAAGCCACCAGGTGTGGCTCTGCCCACGGTCTCGCCCCCTGGTGTG; GATGCCAAAGCCCAGGTGAAGACAGAGACCACAGGCCCCCAGGGACCCCCACACTACACCGACCAGCCGT; CCACTTCCCAGATCGCCTACACTTCCCTCAGTCTGCCCCACTACGGCTCCGCCTTCCCCTCCATCTCACG; ACCCCAGTTTGACTATTCTGACCATCAGCCCTCAGGACCCTATTATGGCCATGCAGGCCAGGCCTCTGGC; CTCTATTCAGCCTTTTCTTACATGGGGCCCTCCCAGCGGCCCCTCTACACTGCCATCTCTGACCCCAGCC; CCTCAGGGCCCCAATCCCACAGTCCCACACACTGGGAGCAGCCAGTATATACGACTCTATCCCGACCTTA; G; ; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT; ACAAGGATGACGACGATAAGGTTTAA
• Restriction Sites: SgfI-MluI
• ACCN: NM_011437
• Insert Size: 1401 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_011437.1, NP_035567.1
• RefSeq Size: 2713 bp
• RefSeq ORF: 1401 bp
• Locus ID: 20665
• UniProt ID: Q04888
• Cytogenetics: 15 37.7 cM
• Summary: Transcription factor that plays a central role in developing and mature glia (PubMed:24204311, PubMed:27532821). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (PubMed:24204311, PubMed:27532821). Once induced, MYRF cooperates with SOX10 to implement the myelination program (PubMed:24204311). Transcriptional activator of MITF, acting synergistically with PAX3 (By similarity).[UniProtKB/Swiss-Prot Function]