Acvr2a (NM_007396) Mouse Untagged Clone

SKU
MC217274
Acvr2a (untagged) - Mouse activin receptor IIA (Acvr2a), (10ug)
  $718.00
In Stock*
Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Acvr2a
Synonyms ActrIIa; Acvr2; TactrII
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC217274 representing NM_007396
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGGAGCTGCTGCAAAGTTGGCGTTCGCCGTCTTTCTTATCTCTTGCTCTTCAGGTGCTATACTTGGCA
GATCAGAAACTCAGGAGTGTCTTTTCTTTAATGCTAATTGGGAAAGAGACAGAACCAACCAGACTGGTGT
TGAACCTTGCTATGGTGATAAAGATAAACGGCGACATTGTTTTGCTACCTGGAAGAATATTTCTGGTTCC
ATTGAAATAGTGAAGCAAGGTTGTTGGCTGGATGATATCAACTGCTATGACAGGACTGATTGTATAGAAA
AAAAAGACAGCCCTGAAGTGTACTTTTGTTGCTGTGAGGGCAATATGTGTAATGAAAAGTTCTCTTATTT
TCCGGAGATGGAAGTCACACAGCCCACTTCAAATCCTGTTACACCGAAGCCACCCTATTACAACATTCTG
CTGTATTCCTTGGTACCACTAATGTTAATTGCAGGAATTGTCATTTGTGCATTTTGGGTGTACAGACATC
ACAAGATGGCCTACCCTCCTGTACTTGTTCCTACTCAAGACCCAGGACCACCCCCACCTTCCCCATTACT
AGGGTTGAAGCCATTGCAGCTGTTAGAAGTGAAAGCAAGGGGAAGATTTGGTTGTGTCTGGAAAGCCCAG
TTGCTCAATGAATATGTGGCTGTCAAAATATTTCCAATACAGGACAAACAGTCCTGGCAGAATGAATATG
AAGTCTATAGTCTACCTGGAATGAAGCATGAGAACATACTACAGTTCATTGGTGCAGAGAAAAGAGGCAC
CAGTGTGGATGTGGACCTGTGGCTAATCACAGCATTTCATGAAAAGGGCTCACTGTCAGACTTTCTTAAG
GCTAATGTGGTCTCTTGGAATGAACTTTGTCATATTGCAGAAACCATGGCTAGAGGATTGGCATATTTAC
ATGAGGATATACCTGGCTTAAAAGATGGCCACAAGCCTGCAATCTCTCACAGGGACATCAAAAGTAAAAA
TGTGCTGTTGAAAAACAATCTGACAGCTTGCATTGCTGACTTTGGGTTGGCCTTAAAGTTCGAGGCTGGC
AAGTCTGCAGGTGACACCCATGGGCAGGTTGGTACCCGGAGGTATATGGCTCCAGAGGTGTTGGAGGGTG
CTATAAACTTCCAAAGGGACGCATTTCTGAGGATAGATATGTACGCCATGGGATTAGTCCTATGGGAATT
GGCTTCTCGTTGCACTGCTGCAGATGGACCCGTAGATGAGTACATGTTACCATTTGAGGAAGAAATTGGC
CAGCATCCATCTCTTGAAGATATGCAGGAAGTTGTTGTGCATAAAAAAAAGAGGCCTGTTTTAAGAGATT
ATTGGCAGAAACATGCAGGAATGGCAATGCTCTGTGAAACGATAGAAGAATGTTGGGATCATGATGCAGA
AGCCAGGTTATCAGCTGGATGTGTAGGTGAAAGAATTACTCAGATGCAAAGACTAACAAATATCATTACT
ACAGAGGACATTGTAACAGTGGTCACAATGGTGACAAATGTTGACTTTCCTCCCAAAGAATCTAGTCTAT
GA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Chromatograms Chromatograms
Sequencher program is needed, download here
Restriction Sites SgfI-MluI |
ACCN NM_007396
Insert Size 1542 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC138823, AAI38824
RefSeq Size 5681 bp
RefSeq ORF 1542 bp
Locus ID 11480
UniProt ID P27038
Cytogenetics 2 28.38 cM
Summary On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6 (PubMed:23527555).UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_007396" in other vectors (4)
SKU Description Size Price
MG219492 Acvr2a (tGFP-tagged) - Mouse activin receptor IIA (Acvr2a), (10ug) 10 ug
$489.00 $916.00
MR219492 Acvr2a (Myc-DDK-tagged) - Mouse activin receptor IIA (Acvr2a) 10 ug
$289.00 $716.00
MR219492L3 Lenti ORF clone of Acvr2a (Myc-DDK-tagged) - Mouse activin receptor IIA (Acvr2a) 10 ug
$1,016.00
MR219492L4 Lenti ORF clone of Acvr2a (mGFP-tagged) - Mouse activin receptor IIA (Acvr2a) 10 ug
$1,016.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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