Rnf26 (NM_153762) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Rnf26 |
| Synonyms | 8030450I18Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | SgfI-MluI | |
| ACCN | NM_153762 |
| Insert Size | 1275 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_153762.3, NP_717095.2 |
| RefSeq Size | 2294 bp |
| RefSeq ORF | 1275 bp |
| Locus ID | 213211 |
| UniProt ID | Q8BUH7 |
| Cytogenetics | 9 A5.1 |
| Summary | E3 ubiquitin-protein ligase that plays a key role in endosome organization by retaining vesicles in the perinuclear cloud. Acts as a platform for perinuclear positioning of the endosomal system by mediating ubiquitination of SQSTM1. Ubiquitinated SQSTM1 attracts specific vesicle-associated adapters, forming a molecular bridge that restrains cognate vesicles in the perinuclear region and organizes the endosomal pathway for efficient cargo transport. Also acts as a regulator of type I interferon production in response to viral infection by mediating the formation of 'Lys-11'-linked polyubiquitin chains on TMEM173/STING, leading to stabilize TMEM173/STING. Also required to limit type I interferon response by promoting autophagic degradation of IRF3.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_153762" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG212563 | Rnf26 (tGFP-tagged) - Mouse ring finger protein 26 (Rnf26), (10ug) | 10 ug |
$657.00
|
|
| MR212563 | Rnf26 (Myc-DDK-tagged) - Mouse ring finger protein 26 (Rnf26) | 10 ug |
$289.00
$457.00
|
|
| MR212563L3 | Lenti ORF clone of Rnf26 (Myc-DDK-tagged) - Mouse ring finger protein 26 (Rnf26) | 10 ug |
$757.00
|
|
| MR212563L4 | Lenti ORF clone of Rnf26 (mGFP-tagged) - Mouse ring finger protein 26 (Rnf26) | 10 ug |
$757.00
|
|
Citations
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