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Htra3 (NM_001042615) Mouse Untagged Clone

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SKU
MC211891
Htra3 (untagged) - Mouse HtrA serine peptidase 3 (Htra3), transcript variant 2, (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $503.00
4 Weeks*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Htra3
Synonyms 2210021K23Rik; 9530081K03Rik; Prsp; Tasp
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC211891 representing NM_001042615
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGCAGGCGCGCGCGCTGCTCCCCGCCACGCTGGCCATTCTGGCCACGCTGGCTGTGTTGGCTCTGGCCC
GGGAGCCCCCAGCGGCTCCGTGTCCTGCGCGCTGCGACGTGTCGCGCTGTCCGAGCCCTCGCTGCCCTGG
GGGCTATGTGCCTGACCTCTGCAACTGCTGCCTGGTGTGCGCTGCCAGCGAGGGCGAGCCCTGCGGCCGC
CCCCTGGACTCTCCGTGCGGGGACAGTCTGGAGTGCGTGCGCGGCGTGTGCCGCTGCCGTTGGACCCACA
CTGTGTGTGGCACAGACGGGCATACTTATGCCGACGTGTGCGCGCTGCAGGCCGCCAGCCGTCGTGCGTT
GCAGGTCTCCGGGACTCCAGTGCGCCAGCTGCAGAAGGGTGCCTGTCCCTCTGGTCTCCACCAGCTGACC
AGTCCGCGGTACAAGTTCAACTTCATCGCCGATGTGGTGGAGAAGATTGCGCCAGCTGTGGTCCACATAG
AGCTCTTTCTGAGACACCCCCTGTTTGGCCGGAATGTGCCGCTGTCCAGTGGCTCGGGCTTCATCATGTC
AGAAGCCGGTTTGATCGTCACCAACGCCCACGTGGTCTCCAGCTCCAGCACTGCCTCCGGCCGGCAGCAG
CTGAAGGTGCAGCTGCAGAATGGGGATGCCTATGAGGCCACCATCCAGGACATCGACAAGAAGTCGGACA
TTGCCACGATTGTAATCCACCCCAAGAAAAAGCTCCCTGTGTTGCTGCTGGGTCACTCAGCAGACCTGCG
GCCTGGCGAGTTCGTGGTGGCCATCGGCAGCCCCTTTGCCCTGCAGAACACCGTGACAACGGGCATTGTC
AGCACTGCCCAGCGGGATGGCAAGGAGCTGGGTCTCCGGGACTCAGACATGGACTATATCCAGACCGATG
CCATCATCAATTACGGGAACTCAGGAGGACCCCTGGTGAACCTGGATGGCGAGGTCATCGGCATCAACAC
GCTCAAGGTTGCAGCTGGCATCTCCTTTGCCATCCCCTCAGATCGCATCACACGCTTCCTCTCTGAGTTC
CAAAACAAGCATGTGAAAGCCCTCTCACCAGCACTGCACTGA

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_001042615
Insert Size 1092 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_001042615.2, NP_001036080.1
RefSeq Size 2209 bp
RefSeq ORF 1092 bp
Locus ID 78558
UniProt ID Q9D236
Cytogenetics 5 B3
Summary Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (PubMed:15206957). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (By similarity).UniProtKB/Swiss-Prot Function
Transcript Variant: This variant (2) lacks several exons and includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform b which is shorter and has a distinct C-terminus, compared to isoform a.
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Documents
Resources
"NM_001042615" in other vectors (4)
SKU Description Size Price
MG226672 Htra3 (tGFP-tagged) - Mouse HtrA serine peptidase 3 (Htra3) transcript variant 2, (10ug) 10 ug
$657.00
MR226672 Htra3 (Myc-DDK-tagged) - Mouse HtrA serine peptidase 3 (Htra3), transcript variant 2 10 ug
$289.00 $457.00
MR226672L3 Lenti ORF clone of Htra3 (Myc-DDK-tagged) - Mouse HtrA serine peptidase 3 (Htra3), transcript variant 2 10 ug
$757.00
MR226672L4 Lenti ORF clone of Htra3 (mGFP-tagged) - Mouse HtrA serine peptidase 3 (Htra3), transcript variant 2 10 ug
$757.00

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