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Cavin4 (NM_026509) Mouse Untagged Clone

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SKU
MC210673
Murc (untagged) - Mouse muscle-related coiled-coil protein (Murc), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $503.00
4 Weeks*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Cavin4
Synonyms 2310039E09Rik; Murc
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>MC210673 representing NM_026509
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGAACACAACGGATCAGCTTCAAATGCTGGTAAAATCCACCAGAATCGGTTGTCAAGTGTGACGGAAG
ATGAAGACCAAGACGCAGCCCTCACCATTGTGACCGTGCTGGACAGAGTGGCCAGTGTCGTGGACAGTGT
GCAGGCAAGCCAGAAGAGAATTGAGGAGAGACACAGAGAAATGGGTAACGCGATAAAGTCTGTCCAAATA
GACCTGCTGAAGCTCTCACAGTCACACAGCAATACGGGCTACGTTGTCAACAAGCTGTTTGAGAAGACCC
GGAAAGTCAGCGCTCACATTAAGGATGTCAAGGCCCGGGTAGAGAAGCAACAGGTTCGTGTAACCAAAGT
CGAAACCAAGCAAGAAGAAATAATGAAGAAAAACAAATTCCGAGTGGTAATCTTCCAGGAGGACATTCCC
TGCCCCGCATCCCTGTCTGTTGTTAAAGACAGAAGCCTGCCCGAGAACCAGGAGGAGGCCGAAGAAGTCT
TCGATCCCCCAATAGAGCTCTCCTCGGATGAGGAGTATTATGTTGAAGAAAGCAGATCTGCCAGGCTTAG
GAAGTCAGGCAAAGAGCACATTGACCACATCAAGAAAGCCTTTTCCAGAGAAAACATGCAGAAGACACGG
CAGACTCTTGACAAGAAAGTGAGTGGGATTAGAACTAGGATAGTCACTCCTGAGAGGAGAGAGAGGCTGA
GGCAGTCGGGAGAGAGGCTGAGGCAGTCAGGAGAGAGGCTGAGGCAGTCGGGGGAAAGATTTAAGAAATC
GATTTCCAGTGCCGCTCCCTCAAAGGAAGCTTTTAAGATTCGGAGCCTTAGGAAAGCGAAGGATCCCAAG
GCCGAGGGCCAGGAGGTAGACAGAGGGATGGGCGTGGACATCATCTCAGGTAGCCTGGCTCTGGGGCCCA
TCCATGAGTTCCACTCTGATGAGTTCAGTGAAACAGAAAAGGAGGTGACCAAAGGAGGGTACAGTCCCCA
AGAAGGAGGGGACCCCCCAACGCCTGAGCCTTTGAAGGTGACTTTTAAACCCCAGGTGAGGGTAGAGGAT
GACGAGTCACTCCTGTTGGAGCTAAAGCAGTCCTCATAG

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI |
ACCN NM_026509
Insert Size 1089 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_026509.3, NP_080785.2
RefSeq Size 2062 bp
RefSeq ORF 1089 bp
Locus ID 68016
UniProt ID A2AMM0
Cytogenetics 4 B1
Summary Modulates the morphology of formed caveolae in cardiomyocytes, but is not required for caveolar formation. Facilitates the recruitment of MAPK1/3 to caveolae within cardiomyocytes and regulates alpha-1 adrenergic receptor-induced hypertrophic responses in cardiomyocytes through MAPK1/3 activation (PubMed:24567387). Contributes to proper membrane localization and stabilization of caveolin-3 (CAV3) in cardiomyocytes (PubMed:26497963). Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway (PubMed:18332105).UniProtKB/Swiss-Prot Function
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"NM_026509" in other vectors (4)
SKU Description Size Price
MG215243 Murc (tGFP-tagged) - Mouse muscle-related coiled-coil protein (Murc), (10ug) 10 ug
$657.00
MR215243 Murc (Myc-DDK-tagged) - Mouse muscle-related coiled-coil protein (Murc) 10 ug
$289.00 $457.00
MR215243L3 Lenti ORF clone of Murc (Myc-DDK-tagged) - Mouse muscle-related coiled-coil protein (Murc) 10 ug
$757.00
MR215243L4 Lenti ORF clone of Murc (mGFP-tagged) - Mouse muscle-related coiled-coil protein (Murc) 10 ug
$757.00

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