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Slc22a2 (NM_013667) Mouse Untagged Clone

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SKU
MC205995
Slc22a2 (untagged) - Mouse solute carrier family 22 (organic cation transporter), member 2 (Slc22a2), (10ug)
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ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $516.00
In Stock*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Slc22a2
Synonyms Oct2; Orct2
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC069911
CTGTAGGTGAAGCCTCAGGATCAGCTGCCTCCAGGAACCATGCCGACCGTGGATGATATTCTAGAACATA TAGGGGAATTCCACCTTTTCCAGAAACAAACATTTTTCCTCTTAGCTCTGCTCTCCGGTGCCTTCACCCC CATCTATGTGGGCATCGTTTTCCTGGGCTTCACCCCCAACCACCACTGCCGGAGTCCTGGAGTGGCCGAG CTGAGCCAGCGGTGTGGCTGGAGCCCAGCAGAGGAGCTGAACTACACCGTGCCGGGCCTGGGGTCTGCGG GTGAGGTCTCCTTCCTCAGCCAGTGCATGAGGTATGAGGTGGACTGGAACCAGAGCACCCTTGACTGTGT GGACCCACTGTCCAGCCTGGCTGCCAACAGGAGCCACTTGCCACTGAGCCCCTGCGAGCATGGCTGGGTG TACGACACTCCCGGCTCCTCCATCGTCACTGAGTTTAACCTAGTGTGTGCTCACTCCTGGATGCTGGACC TGTTTCAGTCATTAGTGAACGTGGGGTTTTTCATCGGTGCTGTGGGCATTGGTTACCTAGCAGACAGGTT TGGGCGGAAGTTCTGCCTCTTGGTCACCATCCTCATCAATGCTATCTCTGGGGTTCTCATGGCGATTTCA CCCAACTATGCCTGGATGTTGGTGTTTCGATTTCTACAGGGACTGGTCAGCAAAGCGGGCTGGTTAATTG GCTATATCCTGATTACAGAATTTGTTGGGCTGGGCTATCGCAGAACAGTAGGGATTTGTTACCAAATCGC CTTTACTGTTGGGCTCCTGATCCTGGCTGGAGTGGCCTATGCCCTTCCCAACTGGAGGTGGCTGCAATTT GCCGTGACTCTGCCCAACTTCTGCTTCCTGCTCTATTTCTGGTGCATACCGGAGTCTCCAAGATGGTTGA TCTCCCAGAACAAAAATGCAAAAGCCATGAAAATCATTAAGCATATTGCTAAGAAAAATGGAAAATCGGT GCCAGTCTCTCTTCAGAGCCTGACGGCAGATGAGGATACTGGCATGAAATTGAACCCTTCGTTCCTGGAC TTGGTCAGAACCCCTCAGATAAGGAAACATACGTTGATCTTGATGTACAATTGGTTCACGAGCTCTGTTC TCTACCAGGGCCTCATCATGCACATGGGCCTCGCAGGGGACAACATCTACTTGGATTTCTTCTACTCTGC CCTGGTGGAATTCCCAGCTGCCTTCATCATCATTCTCACCATAGACCGGATTGGTCGCCGCTATCCCTGG GCTGTGTCAAATATGGTGGCAGGAGCAGCCTGCCTAGCTTCGGTTTTTATCCCTGATGATCTACAGTGGC TGAAAATTACCGTGGCGTGCTTGGGTAGAATGGGCATCACCATAGCCTACGAAATGGTCTGCCTGGTCAA CGCTGAGCTGTACCCCACATACATCAGGAATCTTGCTGTCCTTGTCTGCTCCTCTATGTGTGACATTGGT GGCATCGTCACACCTTTCCTGGTCTACCGTCTCACTGACATCTGGCTGGAGTTCCCGCTGGTCGTATTTG CTGTGGTTGGCCTTGTTGCTGGGGGACTTGTGCTATTGCTACCTGAGACCAAAGGGAAGGCTCTGCCTGA GACCATCGAGGATGCTGAGAAGATGCAGAGGCCAAGAAAAAAGAAAGAAAAGAGAATTTACCTCCAAGTT AAGAAAGCAGAACTAAGCTAAAGAGAAAGAGCATCATTGCTGCTGGAGATGACTTTGCTCTCTCTGAGAC CAGAGGCAGAGCTTCTCTTCCCCTCCCGCGAAAGCCACACAACCCAACCTCACTTACCCCTGAATTCCTG AACTCCATCAGCAGTGAGCTGTCGCCCGCCCAGTTTGTTGCACTGATGTGTCCAGCTCTTCCTCTCAACC AGGACCTCACTCCACCTCACTCCACTCTCAACAGTCCTGGGGAATGCCCATTGCTTTGCTGGATTTGTTG GGGTTTTTTTCATCTGTACATTTCTTTACTTGGTTTCTTTCTCCAAGCATGACATCAAACCAAAATATAC AAGGGAGCTGTGGGTCAGGACAACTAACTATTAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_013667
Insert Size 1662 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC069911, AAH69911
RefSeq Size 2081 bp
RefSeq ORF 1662 bp
Locus ID 20518
UniProt ID O70577
Cytogenetics 17 8.61 cM
Summary Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, dopamine, noradrenaline (norepinephrine), serotonin, choline, famotidine, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-4-(dimethylamino)-styryl-N-methylpyridinium ASP, amiloride, metformin, N-1-methylnicotinamide (NMN), tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, cisplatin and oxaliplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity (By similarity).UniProtKB/Swiss-Prot Function
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Documents
Resources
"NM_013667" in other vectors (4)
SKU Description Size Price
MG208770 Slc22a2 (tGFP-tagged) - Mouse solute carrier family 22 (organic cation transporter), member 2 (Slc22a2) 10 ug
$716.00
MR208770 Slc22a2 (Myc-DDK-tagged) - Mouse solute carrier family 22 (organic cation transporter), member 2 (Slc22a2) 10 ug
$289.00 $516.00
MR208770L3 Lenti ORF clone of Slc22a2 (Myc-DDK-tagged) - Mouse solute carrier family 22 (organic cation transporter), member 2 (Slc22a2) 10 ug
$816.00
MR208770L4 Lenti ORF clone of Slc22a2 (mGFP-tagged) - Mouse solute carrier family 22 (organic cation transporter), member 2 (Slc22a2) 10 ug
$816.00

file-alt Citations

Oxaliplatin-induced neurotoxicity is dependent on the organic cation transporter OCT2
Sprowl, Ciarimboli, Lancaster et al
PNAS (2013) 110 (27), 11199-204 DOI: 10.1073/pnas.1305321110
Cited by 175
AI Summary: OriGene’s TissueScan Colon Cancer Tissue qPCR Panel V array was used in this study to analyze OCT2 expression across various colorectal cancer stages and normal tissues, helping to establish the transporter’s relevance to oxaliplatin-induced neurotoxicity.
Snippet: 48 tissues covering four disease stages and normal colorectal tissue using the TissueScan Colon Cancer Tissue qPCR Panel V array (Origene) and TaqMan ... and in 100 × 60 mm cylindrical tubes before the force necessary for a rigid Von Frey hair filament (IITC Life Science) to
Showing 1-1 of 1 papers.
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