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Ccdc22 (NM_138603) Mouse Untagged Clone

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SKU
MC205725
Ccdc22 (untagged) - Mouse coiled-coil domain containing 22 (Ccdc22), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $585.00
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Ccdc22
Synonyms AI481216; DXImx40e; Ppp1r3f; Sfc22
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC011195
GACCCAGCCCCGGAGTTAGAATTAACTCCACCATGGAGGAGGCTGACCGAATCCTCATCCATTCCTTGCG CCAGGCGGGCACGGCAGTTCCTCCAGAAGTGCAGACTCTGCGAGCTTTCACCACTGAGCTGGTCGTAGAG GCTGTGGTCCGATGCCTTCGAGTGATTAATCCTGATGTGGGCTCTGGCCTCAGTCACTTGCTACCACCAG CCATGTCTGCCCGCTTCCGCCTGGCCATGAGTCTGGCCCAGGCCTGCATGGACCTGGGCTATCCCTTGGA GCTTGGCTATCAGAACTTCCTCTATCCCAGTGAGCCTGACCTTCGAGATCTGCTTCTTTTCTTGGCTGAG CGACTACCCAGCGATGCCTCTGAGGACGCAGACCAGCCTGCAGGTGACTCGGCTATTTTCCTTCGGGCCA TTGGGAGCCAAATCCGGGACCAGCTGGCCCTGCCCTGGGTCCCACCTCTCCTTCGAACTCCCAAGGTGCA GCGCCTCCAGGGCTCAGCCCTCCAGCAGCCGTTCCACTCCAGCAGGTTGGTTCTACCTGAGTTGAATTCC AGCGGAGAGCTATGGGAGTTCCAGGCCAGTCCCCTGCTGCTACCAGCCCCCACACAGGTGCCCCAGCTTC AGGGGAGGGCAGCCTCACTCCTTGAACACCATGCCAGCCAGCTCTGCCAGCATGTGAACAGGGATTGCCC AGGAGATGAAGACCGGGTGCGCTGGGCATCCCGCGTCCCATCCCAGGAGGATTCCCGGGCTCCACAGCAG AGACTGCACAAGCAGCTGATTGAACATCTGCGTCAAAGCTGGGGCCCACTTGGAGCCCCGACACAAGTCC GAGACCTAGGAGAGATGCTGCAGACCTGGGGTGCTAGGGCTATGACTGGTGTGCCCAAAGGCTCCCGCTT CACCCATTCAGAGAAGTTTACCTTCCATCTGGAGCCCCAGGTCCAGGCAGCTCAGGTGGCAGATGTACCA GCTACCTCTCAAAGGCTTGAACAGGACACACGGGCAGCTCAAGAGCAGGAGTTAGAGTCCCTTCGTGAGC AGCTGGCGAGTGTGAACCACAACATTGAAGAGGTTGAAGCTGACATGAAGACCCTGGGAATCAACCTTGT GCAGGTGGAAACCGAGTGCCGACAAAGTGAACTCAGTGTGGCCGAGCAGGAGCAGGCCCTGCGCCTGAAG AGCAGGACGGTGGAATTGCTGCCTGATGGGGCTGCCAACCTCGCCAAACTGCAGCTTGTGGTGGAGAGCA GCGCTCAGAGGCTCATCCATCTAGCAAGCCAGTGGGAGAAACACCGGGTCCCACTTCTTGCTGAGTACCG CCACCTCAGAAGACTCCAGGACTGTAGGGAGCTGGAATCGTCTCGACGGCTGGCAGAAATCCAGGAGCTG CACCACAGTGTTCGAGCAGCTGCAGAGGAGGCTCGCCGGAAGGAGGAGGTCTATAAGCAGCTGGTGTCAG AGCTGGAGACTCTGCCAAAAGATGTGTCCCGGCTGGCCTATACTCAGCGCATCCTGGAGATTGTGGGCAA CATCCGGAAGCAGAAGGAAGAGATCACTAAGATCTTGTCGGACACAAAGGAACTGCAGAAGGAAATCAAC TCTCTCTCTGGGAAGCTCGACCGGACATTTGCAGTGACTGATGAGCTTGTGTTCAAGGATGCTAAGAAGG ATGATGCTGTTCGGAAAGCCTACAAGTACCTAGCTGCCCTGCATGAGAATTGCAGTCAGCTCATCCAGAC CATTGAGGACACAGGCACTATCATGAGGGAAGTTCGAGATCTTGAGGAGCAGATTGAGACAGAGATGGGC AAGAAGACTTTGAGCAACCTGGAGAAGATCTGTGAGGACTACCGAGCCCTTCGCCAGGAGAATGCTGGCC TCTTGGGCCGGGTCCGAGAGGCCTAGAGCCCTGATGGATGTCTCCTAACCACAGGCAGGAATTTGGGGTG CTGGAGACAGTGCTGAGGCACCTGTTCTAGCACTCTCTTTCATTTGGTATCCGCTTTCTCCTGCTGGGAT CTTAAACCCAGCTGTCTGCTTATATGTTCCCATATCTGATCAGGGTGATTGTCCAGCTGACCACAGTTTA TTGGATGGGCACTGGGGGCCAGGGGCCTTGGATCCCAAATAAAAGAGAAGTTCTTCTGTGAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_138603
Insert Size 1884 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC011195, AAH11195
RefSeq Size 2194 bp
RefSeq ORF 1884 bp
Locus ID 54638
UniProt ID Q9JIG7
Cytogenetics X 3.42 cM
Summary Involved in regulation of NF-kappa-B signaling. Promotes ubiquitination of I-kappa-B-kinase subunit IKBKB and its subsequent proteasomal degradation leading to NF-kappa-B activation; the function may involve association with COMMD8 and a CUL1-dependent E3 ubiquitin ligase complex. May down-regulate NF-kappa-B activity via association with COMMD1 and involving a CUL2-dependent E3 ubiquitin ligase complex. Regulates the cellular localization of COMM domain-containing proteins, such as COMMD1 and COMMD10. Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1. Plays a role in copper ion homeostasis. Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes.UniProtKB/Swiss-Prot Function
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"NM_138603" in other vectors (4)
SKU Description Size Price
MG209570 Ccdc22 (tGFP-tagged) - Mouse coiled-coil domain containing 22 (Ccdc22) 10 ug
$785.00
MR209570 Ccdc22 (Myc-DDK-tagged) - Mouse coiled-coil domain containing 22 (Ccdc22) 10 ug
$289.00 $585.00
MR209570L3 Lenti ORF clone of Ccdc22 (Myc-DDK-tagged) - Mouse coiled-coil domain containing 22 (Ccdc22) 10 ug
$885.00
MR209570L4 Lenti ORF clone of Ccdc22 (mGFP-tagged) - Mouse coiled-coil domain containing 22 (Ccdc22) 10 ug
$885.00

file-alt Citations

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