Ptges2 (NM_133783) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Ptges2 |
| Synonyms | 0610038H10Rik; C79137; Gbf1; Mpges2; Pges2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_133783 |
| Insert Size | 1155 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC004846, AAH04846 |
| RefSeq Size | 1598 bp |
| RefSeq ORF | 1155 bp |
| Locus ID | 96979 |
| UniProt ID | Q8BWM0 |
| Cytogenetics | 2 B |
| Summary | The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta. provided by RefSeq, Oct 2009 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_133783" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG205997 | Ptges2 (tGFP-tagged) - Mouse prostaglandin E synthase 2 (Ptges2) | 10 ug |
$657.00
|
|
| MR205997 | Ptges2 (Myc-DDK-tagged) - Mouse prostaglandin E synthase 2 (Ptges2) | 10 ug |
$289.00
$457.00
|
|
| MR205997L3 | Lenti ORF clone of Ptges2 (Myc-DDK-tagged) - Mouse prostaglandin E synthase 2 (Ptges2) | 10 ug |
$757.00
|
|
| MR205997L4 | Lenti ORF clone of Ptges2 (mGFP-tagged) - Mouse prostaglandin E synthase 2 (Ptges2) | 10 ug |
$757.00
|
|
Citations
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