Irf2 (NM_008391) Mouse Untagged Clone

SKU MC205631

Irf2 (untagged) - Mouse interferon regulatory factor 2 (Irf2), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Irf2
• Synonyms: 9830146E22Rik; AI646973; Irf-2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC006577; CGGACGCGTGGGCGGACGCGTGGGTTTCGATCTGGACTGTTCTCAGGCAAGCCGGGGACTAACTTTTAGT TTTGCTCCTGCGATTATTCAACTGACGGGCTTTCATTTCCATTTTACACACCCTAACAACACTCACACCT TGCGGGATTGTATTGGTAGCGTGGAAAAAAAAAGCACATTGAGAGGGTACCATGCCGGTGGAACGGATGC GAATGCGCCCGTGGCTGGAGGAGCAGATAAATTCCAATACGATACCAGGGCTAAAGTGGCTGAACAAGGA GAAGAAGATTTTCCAGATCCCCTGGATGCATGCGGCTCGGCACGGATGGGACGTGGAAAAGGATGCTCCG CTCTTCAGAAACTGGGCGATCCATACAGGAAAGCATCAACCAGGAATAGATAAACCAGATCCAAAAACAT GGAAAGCAAATTTTCGATGTGCCATGAATTCCCTGCCCGACATTGAGGAAGTGAAGGACAGAAGCATAAA GAAAGGAAACAACGCCTTCAGAGTCTACCGGATGCTGCCCTTATCCGAACGACCTTCCAAGAAAGGAAAG AAACCAAAGACAGAAAAAGAAGAGAGAGTTAAGCACATCAAGCAAGAACCAGTTGAGTCATCTTTGGGGC TTAGTAATGGAGTAAGTGGCTTTTCTCCTGAGTATGCGGTCCTGACTTCAGCTATAAAAAATGAAGTGGA TAGTACGGTGAACATCATAGTTGTAGGACAGTCCCATCTGGACAGCAACATTGAAGATCAAGAGATCGTC ACTAACCCGCCAGACATCTGCCAGGTTGTAGAAGTGACCACTGAGAGTGATGACCAGCCAGTCAGCATGA GTGAGCTCTACCCTCTACAGATTTCTCCTGTGTCTTCCTACGCAGAAAGCGAAACTACCGACAGTGTGGC CAGTGATGAAGAGAACGCAGAGGGGAGACCACACTGGAGGAAGAGGAGCATCGAAGGCAAGCAGTACCTC AGCAACATGGGGACACGGAACACCTATCTGCTGCCCAGCATGGCGACCTTTGTCACCTCCAACAAGCCAG ATCTGCAGGTCACCATCAAAGAGGAGAGCTGTCCGATGCCTTACAACAGCTCCTGGCCCCCATTTACAGA CCTTCCCCTTCCTGCCCCAGTGACCCCCACGCCCAGCAGCAGTCGGCCAGACCGGGAGACCCGGGCCAGT GTCATCAAGAAGACATCTGATATCACCCAGGCCCGTGTCAAGAGCTGTTAAGCCTTTGACTCTCCCTGGT GGTTGTTGGGATTTCTTAGCTTTGTGTTGTTCTTTGTTTGTATTATATTATTTTTTTTCTCTATGATACC TATCTTAGACACATCTAAGGGAGAAAGCCTTGACGATAGATTATTGATTGCTGTGTCCAACTCCAGAGCT GGAGCTTCTTCTTAACTCAGGACTCCAGCCCCCCCCCCTCGGTAGATGCGTATCTCTAGAACCTGCTGGA TCTGCCAGGGCTACTCCCTCAAGTTCAAGGACCAACAGCCACACGGGCAGTGGAGGTGCTGCGTTGCCTA CGGTCAAGGCCAGCATGGTGGAGTGGATGCCTCAGAACGGAGGAGAAAATGTGAACTAGCTGGAATTTTT TTATTCTTGTGAATATGTACATAGGGCAGTACGAGCAATGTCGCGGGCTGCTTCTGCACCTTATCTTGAA GCACTTACAATAGGCCTTCTTGTAATCTTGCTCTCCTTCACAGCACACTCGGCGACCCCTTCTGTGTCCA CTACCCCACTACCCACCCCTCCCTCCTCAACCCCTCCATCCCGGTCCTCTATGCGCCCCTTCCCCCCAAC CAATCCCATCACAACCTCTTACCTATCCTTTCCCTCCCAACCCCTTCTATCCCAGCCCACCACCTACCCC ACTCCTCCCCAACTCCTCCATTCTAGCCCATTACCCACGCCTCTCTCCTCAGCCCAGCCTACCCCATCCC ACCCTGTTCCTTTCCTCCAGTTTCCTCTCCTCAAAGGCAAGGCTCTACATCTTGGAGGAGGAGGAGGAGA AGAAAATGAGTTTCTTCACCGCTGTCCCATTTTAAGACTGCTTGAATAATAAAAAAAAAAATCTTTCTAA TCTGCTATGCTTGAATGGCACGCGGTACAAAGGAAAACTGTCATGGAAATATTATGCAAATTCCCAGATC TGAAGACGGAAAATACTCTAATTCTAACCAGAGCAAGCTTTTTTATTTTTTTATACAAGGGGAATATTTT ATTCAAGGTAAAAAAATTCTAAATAAAATATAATTGTTTTTTATCTTTTCTACAGCAAATTTATAATTTT AAGATTCCTTTTCCTGTTCATCAGCAGTTGTTATTACATCCCTTGTGGCACATTTTTTTTTTAATTTTGT AAAGGTGAAAAAAAAACTTTTATGAGCTCATGTAGCAATCAAATTATCCTGTGGATTGATAATAAATGAA TATGGTATATAGTTAAAGATTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_008391
• Insert Size: 1050 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC006577, AAH06577
• RefSeq Size: 2515 bp
• RefSeq ORF: 1050 bp
• Locus ID: 16363
• UniProt ID: P23906
• Cytogenetics: 8 B1.1
• Summary: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.[UniProtKB/Swiss-Prot Function]