Rangap1 (NM_011241) Mouse Untagged Clone

SKU MC204740

Rangap1 (untagged) - Mouse RAN GTPase activating protein 1 (Rangap1), transcript variant 1, (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Rangap1
• Synonyms: C79654; Fug1; mKIAA1835
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC052862; AAGAGGTAATCCGCCGCGGCAGCAAGGAGAGGCAAGCAGACTGGTCACTGGGCCTGGCCCCCACGCGGAC TCTCAAGCAGTGACCGACGCGCGCGTTCCGTCCCCCCACGCCGCGGTGCCGCTAATTTGTGTTTACAGAC CTGCAGGGGAGCCCGCCACTGCAGCCATGGCCTCTGAAGACATTGCCAAACTGGCAGAGACCCTGGCTAA AACTCAGGTAGCCGGAGGGCAGCTGAGTTTTAAGGGCAAGGGTCTCAAACTAAATACTGCAGAAGATGCT AAAGATGTGATTAAGGAGATTGAAGAGTTTGACGGCCTCGAAGCTCTACGATTGGAGGGCAACACGGTGG GCGTGGAAGCGGCCAGAGTCATCGCCAAGGCCTTAGAGAAGAAGTCTGAGCTGAAGCGATGCCACTGGAG TGACATGTTCACAGGAAGGCTTCGGTCTGAGATCCCACCAGCTCTGATCTCACTAGGGGAGGGACTCATC ACTGCAGGAGCACAGCTGGTGGAACTGGACCTCAGTGACAACGCATTTGGACCCGATGGAGTGCGAGGCT TCGAGGCCCTCCTCAAGAGCCCAGCCTGCTTCACCCTACAGGAACTCAAGCTTAACAACTGTGGCATGGG CATCGGGGGTGGCAAGATTCTGGCAGCAGCTCTGACTGAGTGTCACCGCAAGTCCAGTGCCCAAGGCAAG CCCCTGGCCCTGAAGGTGTTTGTGGCTGGCAGAAATCGCCTGGAGAATGACGGAGCCACTGCACTGGCAG AAGCTTTTGGGATCATCGGGACTCTGGAAGAGGTGCATATGCCACAGAACGGAATTAACCATCCTGGTGT CACAGCCCTGGCCCAGGCCTTTGCCATCAACCCCCTGTTGCGAGTCATCAACCTAAATGACAACACCTTC ACTGAGAAGGGTGGGGTGGCCATGGCTGAGACTCCGAAGACTCTGCGACAAGTGGAAGTGATCAATTTTG GAGACTGCCTGGTGCGCTCTAAGGGTGCCGTTGCCATCGCAGATGCTGTCCGTGGTGGCCTGCCCAAGCT AAAGGAGCTGAATCTGTCGTTCTGCGAAATCAAGAGAGATGCTGCCCTGGTTGTTGCTGAGGCTGTGGCC GACAAGGCTGAGCTGGAGAAGCTGGACCTCAATGGCAATGCCCTCGGAGAAGAGGGCTGTGAGCAGCTTC AGGAGGTGATGGACAGCTTCAATATGGCCAAGGTGCTGGCATCCCTCAGTGATGATGAGGGAGAGGATGA AGATGAGGAGGAAGAAGGAGAAGAGGATGATGAGGAGGAGGAAGATGAAGAGGATGAGGAAGATGATGAT GAGGAGGAGGAGGAGCAGGAGGAAGAGGAAGAGCCTCCGCAGAGAGGGTCAGGGGAGGAGCCGGCTACAC CCTTGAGGAAGATCCTGGACCCTAACAGTGGGGAGCCAGCTCCCGTGCTGTCCTCCCCGACTCCCACAGA CCTCTCCACCTTCCTGTCATTCCCCTCCCCAGAGAAGCTGCTGCGTCTGGGTCCCAAGGTCTCGGTGCTG ATAGTCCAGCAGACTGATACCTCCGACCCAGAGAAGGTTGTTTCAGCCTTCCTGAAGGTGGCATCTGTGT TCAGGGATGACGCCTCAGTAAAGACCGCAGTGCTGGATGCCATCGATGCCCTCATGAAGAAGGCCTTCAG CTGCTCCTCTTTCAATTCCAACACCTTCCTTACCAGGCTGCTCATCCACATGGGTCTGCTCAAGAGTGAA GACAAGATCAAGGCCATACCCAGCCTGCATGGCCCCCTGATGGTGTTGAACCACGTGGTGAGGCAGGACT ATTTCCCCAAGGCCCTTGCACCCCTGCTCTTGGCATTTGTGACAAAGCCCAATGGCGCGCTGGAAACCTG CTCCTTTGCCCGCCACAATCTGCTGCAGACGCTATACAACATCTAGATTTAAAGGCAGCTGCTTCTTGTC CCTCGCCCTGCCCCAGTGACTGAGGGTCTTGGGTGGACTGAGCTCGGCCAGCATCTCCATTGGATATTTT GACCAGAGGAAGGGAGAGGGTCTTGTCTCCTGTGTCATATTGGTCCTTTGATACTGTGTTGGTTTGGTGT GTGTGTGTGGGTATGTACTTCCTGTCTGGATTGCAGATCTTCATCTCCCTGCTGGACTAACCCAAGTCCA CTGTGGGGAATTGATGCCTAGGGGAAGGGTAGAAAGCTGCTTTGTTATTAAACTTAGGCCAACTTAGCCA TAGGCCCCGTTGGCTGTCCTGTCTGCCCTGCCTTCCTGTCCCACCAAAGCCTGGGGAATTCTGTGTGCTG TGTCCACCGTGCCTAAATAACAGAGGCTATCAGAGATGGGCTATCATTAGAAAGTAAAACTCAGCCGGGC GTGGTGGCACATGCCTTTAATCCCAGCACTCAGGAGACAGAGGCAGGCAGAATTCTGAGTTTGAGGCCAG CCTGGTCTACAAAGTGAGTTCCAGGACAGCCAGGTCTATACAGAGGAACCCTGTCTCAAAAAAACAAAAA CAAAAAAAAAACCTCTGCCCTTAACCATGTGACTTGGAGGAGCAGCCAGGGGAGTGGGAGCTGTCTGGGG TAACCTGGCTCTAGGACCAGGTGGAAAAAGCACCTTGGCTGGCCCAGCCCTGTTCTTCTCCTGGGGAGGG AAGGGCAGGTCCCCTAATGCCTGAACCACATGTTGGGCCTACTCTCTGAGGGTTTTCTAAGACAGGAGTG TGTAATAGGGATGGAGCCGGGTAAGAGATGCTCTGTGACTTCCCGAAGTGGCTGCTTGGCCACCTCCTAC TTCCCGTTGTGTTGTGTGTCTGGGCTGTGCCTGGGAGCTTCACAAATAAACGTCATCTGTGTAAAAAAAA AAAAAAAAAAAAAAAAAG
• Restriction Sites: RsrII-NotI
• ACCN: NM_011241
• Insert Size: 1770 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC052862, AAH52862
• RefSeq Size: 2888 bp
• RefSeq ORF: 1770 bp
• Locus ID: 19387
• UniProt ID: P46061
• Cytogenetics: 15 38.21 cM
• Summary: GTPase activator for RAN. Converts cytoplasmic GTP-bound RAN to GDP-bound RAN, which is essential for RAN-mediated nuclear import and export (PubMed:18305100). Mediates dissociation of cargo from nuclear export complexes containing XPO1, RAN and RANBP2 after nuclear export (By similarity). Required for postimplantation embryonic development (PubMed:8314081).[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (1) differs in the 5' UTR and has multiple coding region differences, compared to variant 3. These differences cause translation initiation at a downstream AUG and result in an isoform (1) with a shorter N-terminus, compared to isoform 2.