Srsf10 (NM_001080387) Mouse Untagged Clone
SKU
MC204429
Srsf10 (untagged) - Mouse serine/arginine-rich splicing factor 10 (Srsf10), transcript variant 2, (10ug)
$300.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Srsf10 |
| Synonyms | Fusip1; FUSIP2; Nssr; NSSR1; NSSR2; Sfrs13a; SRrp40; Srsf13a; TASR; TASR1; TASR2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_001080387 |
| Insert Size | 786 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC037591, AAH37591 |
| RefSeq Size | 2683 bp |
| RefSeq ORF | 786 bp |
| Locus ID | 14105 |
| UniProt ID | Q9R0U0 |
| Cytogenetics | 4 D3 |
| Summary | Splicing factor that in its dephosphorylated form acts as a general repressor of pre-mRNA splicing. Seems to interfere with the U1 snRNP 5'-splice recognition of SNRNP70. Required for splicing repression in M-phase cells and after heat shock. Also acts as a splicing factor that specifically promotes exon skipping during alternative splicing. Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, prevents SRSF10 from binding to its mRNA-binding sites close to m6A-containing regions, leading to inhibit exon skipping during alternative splicing (By similarity). May be involved in regulation of alternative splicing in neurons (PubMed:10583508).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (2) encodes the longest isoform (2). |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001080387" in other vectors (3)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MR203442 | Srsf10 (Myc-DDK-tagged) - Mouse serine/arginine-rich splicing factor 10 (Srsf10), transcript variant 2 | 10 ug |
$289.00
$300.00
|
|
| MR203442L3 | Lenti ORF clone of Srsf10 (Myc-DDK-tagged) - Mouse serine/arginine-rich splicing factor 10 (Srsf10), transcript variant 2 | 10 ug |
$600.00
|
|
| MR203442L4 | Lenti ORF clone of Srsf10 (mGFP-tagged) - Mouse serine/arginine-rich splicing factor 10 (Srsf10), transcript variant 2 | 10 ug |
$600.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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