Ppp2r5b (NM_198168) Mouse Untagged Clone

SKU MC203522

Ppp2r5b (untagged) - Mouse protein phosphatase 2, regulatory subunit B (B56), beta isoform (Ppp2r5b), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Ppp2r5b
• Synonyms: B'beta; BC026670
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC058977; GCGCCGCCGCCCAGCCCCAGCGCCCCGAGCGGCAGAACCACCGCTAAGGACCCTTGAACCGTCGTCTCTT CCACCGAGGCAACCTCTAGGGTCGGCGACCAAAGTCTGGGTTTCTGAGAAAAGAGCCAGCGTGGGAACCC TGACTGGAACTCTTCTGGATCCCCAGGAAAGACCTGAGCCATTGCCTTTCTACCTTACCTGCCCCCCCAG GACTGGGCAGTTGCCAGAGGCCCTGGGGGGGTCAGGACTGTGGCCGTGCCTCCCCCACCCCCTGAAACAT GCTGGACAGGATGGGTCCCAGTTAGTGTGTGTGGCCTCATTCAACTTACTCCAGACCCACAAGGAGCCCC CTGGGCTCTGAAAGATTGACCCGTGTTGTCCACTGGCCATGGAGACGAAGCTGCCCCCTGCGAGCACCCC CACAAGCCCCTCCTCCCCAGGGCTGTCTCCAGTGCCACCACCAGACAAGGTGGATGGCTTCTCCCGCAGG TCCCTCCGCAGGGCCCGGCCCCGTCGCTCACACAGCTCTTCTCAGTTCCGCTATCAGAGCAACCAGCAAG AGCTCACTCCACTGCCCCTGCTCAAAGATGTGCCAGCCTCTGAGTTGCATGAGTTGCTGAGCCGGAAACT GGCCCAATGTGGGGTGATGTTTGACTTCTTGGACTGCGTGGCTGACCTCAAGGGGAAGGAGGTGAAGCGT GCAGCCCTCAATGAACTGGTGGAATGTGTGGGTTGCACCCGGGGTGTGCTCATCGAGCCCGTCTACCCAG ACATCATCCGCATGATATCAGTAAATATCTTCCGGACCCTGCCACCCAGCGAGAACCCTGAGTTTGACCC TGAAGAAGATGAGCCCAACCTTGAGCCCTCGTGGCCACATCTGCAGCTGGTATATGAGTTTTTCCTGCGT TTCTTGGAGAGTCCAGATTTCCAGCCCTCTGTGGCCAAGAGATACGTGGATCAAAAGTTTGTCCTAATGC TCCTGGAGCTATTTGACAGCGAGGACCCCCGGGAACGTGAGTACCTCAAGACCATCTTGCATCGGGTGTA CGGCAAGTTCCTGGGTCTCCGGGCCTACATCCGCAAACAGTGCAACCACATCTTCCTCCGGTTCATCTAC GAGCTGGAACACTTCAATGGTGTGGCTGAGCTCTTAGAGATCTTAGGAAGCATCATCAATGGCTTTGCGC TGCCCCTGAAGACTGAGCACAAGCAGTTCCTGGTTCGAGTCCTGATCCCCTTGCACTCTGTCAAGTCACT ATCTGTTTTTCATGCTCAGCTGGCATACTGTGTGGTGCAGTTCCTGGAGAAGGATGCAACCTTGACAGAG CATGTTATCCGGGGGCTTCTCAAATACTGGCCTAAAACCTGCACCCAGAAGGAGGTGATGTTCCTGGGGG AGATGGAAGAGATTCTTGATGTCATCGAGCCCTCCCAGTTTGTGAAGATCCAGGAGCCCCTCTTCAAGCA GGTGGCTCGCTGTGTCTCCAGCCCCCATTTCCAGGTTGCAGAGCGGGCTCTGTATTTCTGGAACAATGAG TACATCCTGAGCCTCATTGAGGACAACTGCCACACTGTGCTGCCTGCGGTATTTGGGACCCTCTACCAAG TGTCCAAGGAGCACTGGAATCAAACCATCGTGTCCCTGATCTACAACGTGCTCAAGACTTTCATGGAGAT GAACGGAAAGCTGTTTGACGAGCTCACAGCCTCCTACAAGCTGGAAAAACAACAGGAGCAGCAGAAGGCC CAGGAGCGGCAGGAGCTATGGCGAGGCTTGGAGGAACTGCGGCTACGCCGGCTACAGGGGACCCAAGGGG CCAAGGAAGCCCCCGTCCCACGGCCTACGCCCCAGGTGGCTGCCAGTGGGGGTCAGAGCTAGATACACCT AGAACAGGAGATGCTAAACCCAGAGCTATCAGCCCCTCCATCCCTCTGCCCAGGGGCCCAGTGAGGCCCA CGCCTCCCCGTGGCCTTGCCGGAGTGGCTCTAGGACTCCCTACCAGCCCCGTGGGAACAGCTTTCACGGA GGGGGAAACAAGAAGGCAAGATGGTAGTCTTGGCAGCAGAACTCTCAGGCCTTTGTGGCAAGATTCTGGC AAGACTAGACCAGGGCAAGTATGCAACTGGGAAGCTGCCATCAGGGATCCTCCCCTGCCCTACACAGCCA GGCTCCAGGCGGCAGCTAGGCCTCTACCCCTGCTCCCAGCCTGGGGCATGGACACTCAGCGCCTGGCCAG GGCCTTCCTCATCCCCACCATGGGGGCACAGTCTATTTATTCTGCCCAGCTCACCCCCAACAAGACCTTG TCCAGGGACATTCTCCTATCCTCTCCCTGGCCCTGACTCCCTTATCCCCTTTTTATTTATTGGGCAGGGG GAGGGGTGAGGGCACAGGCAAGAAGATTCACATTGTCCTGGGGTGAGGGGGGAGGTCACAGTAATCATGG TCTGCCCCCTTCACCTGGCTGGGGGCAGATTTAATAAAGAGCGAAACTCAAAAAAAAAAAAAAAAAAAAA AAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_198168
• Insert Size: 1494 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC058977, AAH58977
• RefSeq Size: 2524 bp
• RefSeq ORF: 1494 bp
• Locus ID: 225849
• UniProt ID: Q6PD28
• Cytogenetics: 19 A
• Summary: As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation.[UniProtKB/Swiss-Prot Function]