Spire2 (NM_172287) Mouse Untagged Clone
$658.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Spire2 |
| Synonyms | BC026502; Spir-2; Spir2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_172287 |
| Insert Size | 2157 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC049152, AAH49152 |
| RefSeq Size | 2399 bp |
| RefSeq ORF | 2157 bp |
| Locus ID | 234857 |
| UniProt ID | Q8K1S6 |
| Cytogenetics | 8 E1 |
| Summary | Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament (PubMed:21620703, PubMed:21983562). Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport (PubMed:21983562). Required for asymmetric spindle positioning and asymmetric cell division during oocyte meiosis (PubMed:21620703). Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis (PubMed:21620703). Also acts in the nucleus: together with SPIRE1 and SPIRE2, promotes assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_172287" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG210260 | Spire2 (tGFP-tagged) - Mouse spire homolog 2 (Drosophila) (Spire2) | 10 ug |
$858.00
|
|
| MR210260 | Spire2 (Myc-DDK-tagged) - Mouse spire homolog 2 (Drosophila) (Spire2) | 10 ug |
$589.00
$658.00
|
|
| MR210260L3 | Lenti ORF clone of Spire2 (Myc-DDK-tagged) - Mouse spire homolog 2 (Drosophila) (Spire2) | 10 ug |
$958.00
|
|
| MR210260L4 | Lenti ORF clone of Spire2 (mGFP-tagged) - Mouse spire homolog 2 (Drosophila) (Spire2) | 10 ug |
$958.00
|
|
Citations
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
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