Mafb (NM_010658) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Mafb |
| Synonyms | kr; Kreisler; Krml; Krml1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_010658 |
| Insert Size | 972 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC038256, AAH38256 |
| RefSeq Size | 3271 bp |
| RefSeq ORF | 972 bp |
| Locus ID | 16658 |
| UniProt ID | P54841 |
| Cytogenetics | 2 80.92 cM |
| Summary | Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter. Involved either as an oncogene or as a tumor suppressor, depending on the cell context.UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
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Resources
"NM_010658" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG204681 | Mafb (tGFP-tagged) - Mouse v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb) | 10 ug |
$489.00
$530.00
|
|
| MR204681 | Mafb (Myc-DDK-tagged) - Mouse v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb) | 10 ug |
$289.00
$330.00
|
|
| MR204681L3 | Lenti ORF clone of Mafb (Myc-DDK-tagged) - Mouse v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb) | 10 ug |
$630.00
|
|
| MR204681L4 | Lenti ORF clone of Mafb (mGFP-tagged) - Mouse v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) (Mafb) | 10 ug |
$630.00
|
|
Citations
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