Igf2bp3 (NM_023670) Mouse Untagged Clone

CAT#: MC202512

Igf2bp3 (untagged) - Mouse insulin-like growth factor 2 mRNA binding protein 3 (Igf2bp3), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Igf2bp3
• Synonyms: 2610101N11Rik; AA522010; AL022933; AU045931; IMP-3; IMP3; Koc13; mimp3; Neilsen
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC049082 sequence for NM_023670
  GGTTTTCGCCCGCCGCTCCCGTGCTTGGGTCACTGTGTGGGTTTGAAAGCCAAGAGGAGAGGAACAAAAT CCACCGGCTCCATCCTCCGCCGTGGGTGCTTTTTTTAATTTAGCATTTTCCTCGGGTTTTAAAACGACCC CTTTTCACAATGAACAAATTGTACATCGGGAACCTCAGCGACCACGCCGGCCCCGCGGACCTGGAAAGTG TCTTCAAGGACGCTAAGATCCCGGTGGCGGGCCCCTTCCTGGTGAAGACGGGCTACGCGTTCGTGGACTG CCCGGACGAGGGCTGGGCCCTCAAGGCCATCGAGGCGCTTTCAGGTAAAATGGAACTACATGGGAAACCG ATGGAAGTTGAGCACTCGGTCCCTAAACGGCAGAGGATTCGTAAACTTCAGATACGAAATATCCCGCCCC ACTTACAATGGGAGGTGCTGGATAGTTTACTAGTCCAGTATGGAGTGGTGGAGAGCTGTGAGCAAGTGAA CACGGATTCGGAAACGGCAGTTGTAAATGTAACCTATTCCAGTAAGGACCAAGCTAGACAAGCCTTAGAC AAACTGAATGGATTCCAGTTAGAGAACTTCACCTTGAAGGTTGCCTACATCCCAGATGAAACTGCTGCCC AGCAAAATCCCTCGCCACAGCTCCGGGGGCGCCGGGGGCCAGGGCAGCGGGGCTCATCCAGGCAGGCGTC TCCAGGATCGGTGTCCAAGCAGAAACCCTGTGACCTGCCACTGCGCCTGCTGGTTCCCACCCAGTTTGTT GGAGCCATTATAGGAAAAGAAGGTGCTACCATTCGCAACATCACAAAGCAGACCCAGTCTAAAATCGATG TCCATCGTAAGGAGAATACAGGGGCCGCGGAGAAGTCCATTACTATCCTCTCTACCCCTGAAGGCACCTC TGCAGCTTGTAAGTCTATTCTGGAGATTATGCATAAGGAAGCTCAAGATATAAAATTCACAGAGGAGATT CCCTTGAAGATCTTAGCTCACAATAACTTTGTAGGCCGTCTCATTGGTAAAGAAGGAAGAAACCTTAAAA AAATCGAGCAAGACACGGACACTAAAATCACAATATCTCCATTGCAGGAACTGACGCTGTACAATCCGGA ACGCACCATTACAGTGAAAGGCAGTGTTGAGACGTGTGCCAAGGCGGAGGAGGAAATAATGAAGAAGATC AGGGAGTCTTATGAAAATGATATTGCTTCCATGAATCTTCAAGCACATTTAATCCCTGGATTAAATCTGA ATGCCTTGGGTCTGTTCCCACCCACGTCAGGGATGCCACCTCCCACCTCAGGGCCCCCTTCAACCCTGAC TCCTCCCTACCCACAATTTGAGCAATCAGAGACGGAGACTGTGCATCTGTTTATTCCCGCCCTGTCCGTT GGCGCCATCATTGGCAAGCAGGGCCAACACATCAAACAGCTTTCTCGCTTTGCGGGAGCTTCGATTAAGA TCGCTCCAGCCGAAGCACCAGATGCTAAAGTGCGGATGGTGATTATCACTGGACCACCAGAGGCTCAGTT CAAGGCTCAGGGAAGAATTTATGGAAAAATTAAAGAAGAAAACTTTGTTAGTCCTAAAGAAGAGGTGAAA CTTGAAGCTCACATCAGAGTGCCGTCCTTTGCTGCTGGCAGAGTTATTGGGAAAGGAGGCAAAACGGTGA ATGAGCTCCAGAGTTTATCAAGTGCTGAAGTTGTCGTCCCCCGTGACCAGACACCTGATGAGAATGATCA AGTAGTTGTCAAAATAACTGGCCACTTCTATGCTTGCCAGGTTGCCCAGAGGAAAATTCAGGAAATTCTG ACTCAGGTAAAGCAGCACCAGCAGCAGAAAGCTCTGCAGAGTGGACCACCTCAGTCAAGGCGGAAGTAAA GGCTCAGGAGACAGCCACCACAGAGGCAGATGCCAAACCAAAGACAGATTTGCTTAACCAACAGACGGGT GCTGACCCATCCAGAACCACGTGCACGAGTTTTTACCTAGCTGGTTGTTTCCGAGGACCAGGCACTCGAT CCTGTCTCTGTGAGAATGTATACTTTATGCTCTCTGAAATATATGACACCCAGCTTTAAAAAAAAAAAAA AAAAAAAAAAAAAAGTGGGGGTAAGGAAAGAGAACTCTGCACTTCCCTTGTGATATCAAAGTATAACAAA CGTGCTAATTTTTCTTAATATCCCTCTATAATGCCAGAAATTGGCATAAATGGTACATTCACTAAATTTA TCAAATAAATTTAAAACTAGATTGTTCCTAAGTCCAATTGTTGAAATTGGATCAAAGTAGAATTGTCAGA GGAACACAACATTAAGCCATTAGAATAGAAGAGCTGTTGTCTCCTGTTTCTCTAACACTAACATGGATAA CCTAAGGGAAGTGCCAGCCGCTGTTGGCAGGGTATTAAACGTGCATTTTTACTCAACTACCTCAGGTATT CAGTAATACAGTTAAAAGCAAAATTATTCCTTTTTTGAAAATTTTATATACTTTATAAAAACTCCAACCG TTTTTTTAAAAAAAATAAAATTTAACAGTTATCAGCTGATAGGCAAGTCATTGAAAAAGTAATTTTACGT CTGGCTGGTGAGAGTAAAGTTGGAAAAATAATTTTGCATTTTTTGAGCCTTTGAAAGTTGGAAAGTCCAC TAACTGTTCAAAGATAAGGAGCAGTGCCTATTCTCAAGAGCAGCCATGCCATGTACTCCTTTGTTCCTAT CTGGGAAGGTTGTTGACGGTACTGACCAAGCAGGCAGGGGCTGGGACGGCCAGTGTACAGGACAGCTAGG GTAAAGGACAGCTAGTGTACAGGGCTCCAGGAGACTTGGGGATTTGTGTTTAGCTATGTGTGGGAATTTG CAAATGCTTTGTGCTTTGACTGTCACCACGAAAAGGAAGAAATTCATGTCAGTGAAGAAATGCAGAATTT AAACAAAATCAGCTTGAGTTTGTTTTACCAGATGCTCAGCTTGCTAACACACTTGAGATCAGACCATACT CTGAGCAGACATGGAAAGGATTGCTTTGTGAAGACCAGGGGGAGTCAGGTGGTATGACAGGGCCGAAGGG CAACAAAATCTCCATTTCCTTGTGCCTGGCACTGTCTCGAGCCTAAGCTATTTTAAAGATGTTTTAAACA GTGGAAGAATTAAGTCCACCAAAAGTCTTCCATGAAATGTAGCAGAGTTTCTGTCTGCCCTGCATTACCT GCCAGCGAGTCAAGGTAGGGGATCCAGCAAACGGTTTTGGGAATTCAGACTGTGGAAACATCGGACTTCC CTTTGCCCTTCCTCAACTTAGTGGCAAAGCCCTGTATGGATACTTGTAGGTGCGGGTGATCCTCAAGGCC ATGCTGCTTTCTGAGTTGTTCTTGTTGCTTTGTTCATAATGTGGTTACAGTCATATTACACTGACCCTGA GGGTATTATGTAACCCTTCAGAAAACCACTTTGCCTCATTGTGTTTCAGGATTAACTTCTACATGCCTTT AAGTTTTTCTGAGTATCAGCATATCATTTAGACATTGTGAAAATGAATTCCTAAACATTTTCATAAAACC GGTTAATTTTGTAGTTTTAGCCAAAAAGTGCCCCCTTTTTACAACTGAATTCATCTAGCATTTTCATATG GTGGATTTAAACTGCTTAAAAAAGAAAATGTGACCGGCTCTCCTGCTTGGGTCTCAGGGGAGATATGCTT AAGGCCAGAGCTCTTCCTCAGTATTTGATTTTTCCAGTGTTTGTTTTTTAAAAAACTGACAGGTGCTACA TTTCTATCTGTTGGTTTCAATTCTGCCATATTTCATGTCTAGCCTTTAGAGTGGCCAATCATGTTTTACT TTCATTTAAGCACTGGTAGTCTGGAGTACCTGGTACTGAGTAACTCTATAATTGTGTTTTGTGTTCACCA TATACAGATCATTTCTCATCTGTAGTGTGCCCCAAATGCAGCTTCACTTTCCAGGTACCCTGATGCAGAA TAAAGTTTTCATCATAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_023670
• Insert Size: 1740 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC049082, AAH49082
• RefSeq Size: 4030 bp
• RefSeq ORF: 1740 bp
• Locus ID: 140488
• UniProt ID: Q9CPN8
• Cytogenetics: 6 23.82 cM
• Gene Summary: RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation. Binds to the 3' UTR of CD44 mRNA and stabilizes it, hence promotes cell adhesion and invadopodia formation (By similarity). Binds to beta-actin/ACTB and MYC transcripts (By similarity). Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs.[UniProtKB/Swiss-Prot Function]