Arl6ip1 (NM_019419) Mouse Untagged Clone

SKU MC202510

Arl6ip1 (untagged) - Mouse ADP-ribosylation factor-like 6 interacting protein 1 (Arl6ip1), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Arl6ip1
• Synonyms: Aip-1; AIP-6; AL022945; Arl6ip; ARMER; AU042858; C85138; mKIAA0069
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC046792 sequence for NM_019419; GGGATAGTGTGTGTTCGCTCGTTGATAACCGCGAGTCTGGAACGATGGCGGAGGGGGATAACCGCAGCAG CAACCTGCTGGCCGTGGAGACTGCAAGTCTTGAAGAGCAGCTGCAAGGCTGGGGAGAGGTGATGCTGATG GCTGACAAAGTCCTTCGATGGGAAAGAGCCTGGTTTCCACCTGCCATCATGGGTGTGGTTTCCCTGCTGT TCCTGATTATCTATTATCTCGATCCATCTGTGCTGTCTGGTGTTTCCTGCTTTGTTATGTTTTTGTGCCT GGCTGACTACCTTGTTCCCATTCTAGCACCAAGAATTTTTGGCTCTAATAAATGGACCACTGAACAACAG CAAAGATTTCATGAAATCTGCAGTAATCTAGTAAAAACTCGACGCAGAGCTGTGGGCTGGTGGAAACGCC TCTTTTCCCTAAAGGAAGAAAAGCCTAAAATGTACTTCATGACCATGATCATTTCTCTTGCTGCGGTGGC TTGGGTGGGACAGCAAGTTCACAACCTGCTTCTCACCTACCTGATTGTGACATTTGTGCTGTTGCTTCCT GGACTAAACCAACATGGGATCATTCTGAAGTACATTGGAATGGCCAAAAGGGAGATAAACAAACTTCTCA AGCAAAAAGAAAAGAAAAATGAGTAGTGTGGCTGCCGCGGAGTGTGCCCTGGCCCTGGGCACTGAAGTGT TACAGTGGCTCGTTGCTTCCCTCACTCTGCCCTTGTTAATAGAAATTCTCACAGGCCAGGCTCTGTGCGG GCTCTAGTGCCAGGTGTAGCTGGGTACATTCCCCGTCAGTGTGACTTCCTTTCATTTTGACAACTTCCTT CCTTTAAGATGCTAAGTGGTGAACTTTACTGTTTTGTACAGTGAACTGTGACTTTGTTGATGTTTGCTTT AGCTATATTCAAGGCAGTGGTCTGTGGCTACAGGAAGCTGGTTCTACTGTCTGCTTAACAAACTGTCTTT GTGAGTACAGAGATTGGGTTTACCACTTCTGCTGAGGAGACCACTTAAAATTCATTCCTGAGTTTCCACT GTGGGAGAATACCCATGGAATAAGATAAAAAATTAATTCCACACCCTAGTGTGTGTAAGTTCCTCGCTCA TAGGAAATGCAACAGTTTGAGGGAGCATTGCCCCTTTGTTCCTGTGAGGACTGGCAGGCTTTGACTGACC TCTCATTCCCTTTGCACTGCTTCAGGTTAGTTCTAGTCCATAATGGCCTTTGAGCAGCAAGCTTTCAGAA GATTATATTTGAGGATTGTAGCAGTTTCTTTGTTTCAGATTGTCAGCTGACTTAAAATGTTTGTGACTTT CCTGTAAGGGCAGCCAGGGATAAAAGTATCCTTTGTTCAATGAGTAGAAAACTAGATTATCTATTAATAT TTAAGACCAGGAAAAAAAAAAAAGAGGCTTAAGAGTAAGCCTGGAAAATCTCACTTGTTTTCGTAGTATT GGCTGTATTTCAGTGCCTCCAGCTTTGCACTTGAGAGACAAGTGTTTACTGCTGTTTGACTTTCCCCTTG ACATTTCTCAGAAAAATGCAGGGCTGCAGCTGAGAGCAGACTGCTGATTGGTGACTCTGGTCTGCCTAGC TTTTGCAACTCTTTAAGCTTACTGTGATCACGTGCCCTCTCAGTAGGGGGCTTTTAGAGCAGTTGAAATC TGCAGAACTGAACCTCTGAGGGCCAAAATAGGACATTTGGGAACAACTCCTTAACCCATGAACTAGCTGT AACATAGTTTGTGGATCCATGCACTGATGCTGTGAAGCCTGCCCCTGTGTGTATCTGTTCTCTCACCTCC CTAGCACTGTAAGCAGCGGTGCCTCTTGTAGCATGTGTGTTTGTTTTTTAATGTTTCATGACTCCCACTT TGATTTTACATGTTTTCTTGTAAATAAGCCTGCCTTCCTACCTGGAATTTGTGTGTGTGTGACTAATACA TGTTCTACGAGTTAACTACTTTGGCAGTTTTAATCATTTCTTCTTTGTTTTGTGGTAAAGGGGAAAAATT AAAAACCAGTTGGAACCCTTTTGTCTCAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: AscI-NotI
• ACCN: NM_019419
• Insert Size: 612 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC046792, AAH46792
• RefSeq Size: 2079 bp
• RefSeq ORF: 612 bp
• Locus ID: 54208
• UniProt ID: Q9JKW0
• Cytogenetics: 7 F1
• Summary: Positively regulates SLC1A1/EAAC1-mediated glutamate transport by increasing its affinity for glutamate in a PKC activity-dependent manner. Promotes the catalytic efficiency of SLC1A1/EAAC1 probably by reducing its interaction with ARL6IP5, a negative regulator of SLC1A1/EAAC1-mediated glutamate transport (PubMed:18684713). Plays a role in the formation and stabilization of endoplasmic reticulum tubules. Negatively regulates apoptosis, possibly by modulating the activity of caspase-9 (CASP9). Inhibits cleavage of CASP9-dependent substrates and downstream markers of apoptosis but not CASP9 itself. May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation (By similarity).[UniProtKB/Swiss-Prot Function]