Sh2d2a (NM_001025571) Mouse Untagged Clone

SKU MC201383

Sh2d2a (untagged) - Mouse SH2 domain protein 2A (Sh2d2a), transcript variant 2, (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Sh2d2a
• Synonyms: Lad; Ribp; Tsad
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC034847 sequence for NM_001025571; TGAGCAGCTGCCGAGTGTGCACCTCCTTTGAGAGCACCCACACCTGCTTCCATGGAGTTCTGCTTGGCCC AACCATGCCCCCAAGGGAATCATGAAGCTACTTCATCAACCTTCAACACCTTCCAGCCAATGAACCTGAC CCAGGGGAGATGCCAGAACTTGAGTTGTGGGAGCAGGCCCAGCATGCAAGTTATGAAGGAACAGGGGGTT CAGCTCAGCCCCAGAACTAACCACACGGTGGTCTCTGCCTCAGCCCCAGGAACTGCCTGGGTCCTAGGGA ATGCCGATAGGGCAGAAGAGGTGCCTGGGAAAGGTGACCTGTCATTGCAAGCTGAGACCAGAGCATGGGT CCAGAAGACCCAGGCCCACTGGCTCTTGCTCAAGACTGCCCCTCTTTGGTTCCATGGCTTCATCACCAGA AGGGAAGCCGAGAGGCTGCTGCAGCCCCAGCCTCTAGGATGCTATCTGGTGCGCTTCAGCGAGAGTGCTG TGACCTTCGTGCTGTCCTACAGGAGCCAGACCTGCTGCCGTCACTTCCTCCTCGCGCAGCTAGGGGATGG GCGCCACGTGGTGCTAGGTGAAGACAGTGCCCATGCGCAGCTTCAGGACCTGCTTGAACATTACACAGAG TGCCCCCTCAGCCCCTACGGAGAGATACTCACCCAACCCCTCGCTCGACAGACAGCTGAGCCTGCTGGAC TTTCCCTAAGGGCTGATTCAGACTCTGGAAGCAAAAGACAGGACCCAGACACCCAGCTCAGCCTGCTCCT CCAACAGGGCCAGGCCCAGGCCTCAGGACACACAGAGAAAACATCCCAGGCATCCAGACCCAGGCCGCCC ATCCCCGCCAAGCCTCAGCTTCCTCCTGAAGTCTATACAAGTCCTGCTTCACGACTGCATCAGGCCCCAC CCATTAACCCCATCTACCAGGAGCCTGATGAACCCATAGCCTTCTATGCCATGGGGCGGGGCAGCCCTGG GGACGCTCCTAGTAATATCTATGCTGAGGTGGAAGGGCCATCGGGAACGGCGCCCATTGGACACCCCATC CTCCGAAAGTGCTGGTCCAGGCCTATCTCAAGAGGCCAGGTAAGGGAGGTACAGGGAAAGATAAGCTCAA GGAGTCGAGCAGAAAGAGGGAGCCCCTCCTGAATATCGGGCAAGGTGAAGGTCAGCAGGCTGAAGCGAGA TGGAGTGTTCCACGCTGCCGAAAACCTTTGCCCAGCTCCAGGCCTAAGGCTCTTCCTGGACATTCACGTG GACTCAGCTTTGTCAAGCCCTACCTGCCCCTACTTCAGGTTTCCTTCAACCACTCTCCATCCCAGGCTGC CTCTCATTGGTCAGGCCTTCCTCACACACATGTGACACTGACCCAGCTCCCTGGAGAGCGTCACTGCCAG TGGGCTCAGAGGAGGAGGCTGCCACACTGTGTGCTCACCCTCACAGTTTCCCCACAGAGTTTCAGTCATG TCTGAATGTGGTATTACTATTAAAGGAGTCAGACTCTTAAAAAAAAAAAAAAAAAAA
• Restriction Sites: EcoRI-NotI
• ACCN: NM_001025571
• Insert Size: 1101 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC034847, AAH34847
• RefSeq Size: 1527 bp
• RefSeq ORF: 1101 bp
• Locus ID: 27371
• Cytogenetics: 3 38.78 cM
• Summary: Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in p56-LCK-mediated T-cell signaling. Could be involved in the regulation of responses to T-cell activation stimuli, specifically proliferation and lymphokine production. Interactions with ITK and TXK may provide important biochemical links of these two important kinases with other components in the T-cell activation machinery.[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.