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Thoc3 (NM_028597) Mouse Untagged Clone

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SKU
MC201308
Thoc3 (untagged) - Mouse THO complex 3 (Thoc3), (10ug)
Interest in protein/lysate? Submit request here!
ORF Plasmid:
Tag Free tGFP DDK
AAV Particle:
DDK
  $457.00
In Stock*
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Specifications
Specifications
Product Data
Type Mouse Untagged Clone
Target Symbol Thoc3
Synonyms 2410044K02Rik; AL033344
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
Fully Sequenced ORF
>BC019603 sequence for NM_028597
GGGAGGCATGGCGGCGCCCGCTGCGGTCCTGGGCCCCTCGGCCCTCGGCCAGAGCGGCCCCGGCTCGATG GCGCCCTGGTGCTCAGTGAGCAGTGGCCCGTCTCGTTACGTGCTCGGGATGCAGGAGCTCTTCCGAGGCC ACAGCAAGACGCGCGAATTCCCGGCGCACAGTGCTAAGGTGCACTCGGTCGCCTGGAGCTGCGATGGCCG TCGCTTGGCCTCGGGGTCCTTCGACAAGACTGCCAGCGTGTTCTTGCTGGAGAAGGACCGGCTGGTCAAA GAAAACAACTACCGGGGCCACGGAGATAGTGTGGACCAGCTTTGTTGGCACCCAAGCAACCCTGACCTCT TTGTCACCGCATCTGGAGATAAAACCATTCGCATCTGGGATGTGAGGACTACAAAATGCATCGCCACTGT GAATACGAAAGGGGAGAACATTAACATCTGTTGGAGTCCCGACGGGCAGACCATCGCTGTGGGCAACAAG GACGACGTTGTGACTTTCATTGACGCCAAGACACACCGCTCCAAAGCGGAGGAGCAGTTCAAGTTTGAGG TCAATGAGATCTCATGGAACAACGACAACAACATGTTCTTCCTGACCAACGGCAATGGTTGCATCAACAT CCTCAGCTACCCAGAATTGAAGCCTGTGCAGTCCATCAATGCCCATCCTTCTAACTGCATCTGTATCAAG TTTGACCCCATGGGGAAATACTTTGCCACAGGAAGTGCAGATGCCTTGGTCAGCCTTTGGGACGTTGACG AGTTAGTGTGCGTGCGGTGCTTTTCCAGACTAGATTGGCCTGTGAGGACCCTCAGTTTTAGCCACGATGG GAAAATGCTGGCATCGGCTTCGGAGGACCATTTCATTGATATAGCTGAAGTCGAGACAGGAGACAAGCTA TGGGAGGTGCAGTGTGAGTCCCCGACTTTCACTGTGGCTTGGCACCCCAAGAGGCCTCTGCTGGCTTTTG CCTGTGATGACAAAGATGGCAAATACGACAGCAGTCGGGAGGCTGGAACTGTGAAGCTGTTTGGACTTCC CAATGACTCCTGAGAGGGCCGACAGCGAGAGGAGAGAGGAGGCAGGAGGCCGGGCGGACTATTTGGGCTA CCTAATGACTGTACCTTTCAGGGAGAGGAGGCCTGGGCTTCCTAATGACTCCTGAGAGGACCTGATGGGA GAGGAGGCTGGGTGCAGACCTTCCTTTTGTATAGTTCAATGTAGTCTTTTGGACTTGTAGGCACCATAAA TGTTTATAAATGTCATAAATGACCAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI |
ACCN NM_028597
Insert Size 1056 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq BC019603, AAH19603
RefSeq Size 1300 bp
RefSeq ORF 1056 bp
Locus ID 73666
UniProt ID Q8VE80
Cytogenetics 13 B1
Summary Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity).UniProtKB/Swiss-Prot Function
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"NM_028597" in other vectors (4)
SKU Description Size Price
MG205327 Thoc3 (tGFP-tagged) - Mouse THO complex 3 (Thoc3) 10 ug
$657.00
MR205327 Thoc3 (Myc-DDK-tagged) - Mouse THO complex 3 (Thoc3) 10 ug
$289.00 $457.00
MR205327L3 Lenti ORF clone of Thoc3 (Myc-DDK-tagged) - Mouse THO complex 3 (Thoc3) 10 ug
$757.00
MR205327L4 Lenti ORF clone of Thoc3 (mGFP-tagged) - Mouse THO complex 3 (Thoc3) 10 ug
$757.00

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