Irf8 (NM_008320) Mouse Untagged Clone

SKU MC200891

Irf8 (untagged) - Mouse interferon regulatory factor 8 (Irf8), (10ug)

Product Data

• Type: Mouse Untagged Clone
• Target Symbol: Irf8
• Synonyms: AI893568; IC; Ics; ICSBP; Icsbp1; IRF; IRF-8; My; Myls
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC005450 sequence for NM_008320; CCGGAGGCGCGGGCAGCGTGGGAACCGGCGGCAGGATGTGTGACCGGAACGGCGGGCGGCGGCTGCGGCA GTGGCTGATCGAACAGATCGACAGCAGCATGTACCCGGGGCTGATCTGGGAAAATGATGAGAAGACCATG TTCCGTATCCCCTGGAAGCATGCCGGCAAGCAGGATTACAATCAGGAGGTGGATGCTTCCATCTTCAAGG CCTGGGCAGTTTTTAAAGGGAAGTTTAAAGAGGGAGACAAAGCTGAACCAGCCACGTGGAAGACGAGGTT ACGCTGTGCTCTGAACAAGAGCCCAGATTTTGAAGAAGTGACTGACCGGTCCCAGCTGGACATTTCTGAG CCATATAAAGTTTACCGAATTGTCCCCGAGGAAGAACAAAAATGCAAGCTGGGCGTGGCACCTGCAGGCT GCATGAGCGAAGTTCCTGAGATGGAGTGTGGCCGCTCAGAGATTGAGGAGCTGATCAAGGAACCTTCTGT GGATGAGTACATGGGTATGACCAAGAGGAGCCCATCCCCACCAGAGGCCTGCAGGAGCCAGATCCTCCCT GACTGGTGGGTCCAGCAGCCCAGTGCAGGCCTGCCACTGGTGACCGGATATGCCGCCTATGACACACACC ATTCAGCTTTCTCCCAGATGGTCATCAGCTTCTACTACGGGGGCAAGCTGGTGGGCCAGGCCACCACCAC CTGCCTTGAAGGCTGCCGTCTCTCCCTGAGCCAGCCGGGGCTGCCTAAGTTGTATGGGCCGGATGGCCTG GAACCCGTGTGCTTTCCGACGGCCGACACCATCCCCAGTGAGCGGCAGAGGCAGGTGACCCGGAAGCTGT TTGGGCACCTGGAACGTGGCGTGCTACTGCACAGCAACCGCAAGGGCGTGTTCGTGAAGCGGCTGTGCCA GGGCCGCGTGTTCTGCAGCGGCAACGCGGTGGTGTGCAAGGGCAGGCCCAACAAGCTGGAGCGGGACGAG GTGGTGCAGGTCTTTGACACCAACCAGTTCATCCGAGAGCTGCAGCAATTCTACGCCACCCAGAGCCGCC TACCTGACAGCAGGGTGGTCCTGTGCTTCGGGGAGGAGTTTCCGGACACTGTGCCCTTGCGCTCCAAACT CATTCTGGTGCAGGTAGAGCAGCTGTATGCCAGGCAGCTGGTGGAGGAAGCGGGCAAGAGCTGCGGTGCT GGCTCCCTGATGCCAGCCCTGGAGGAGCCCCAGCCGGACCAGGCTTTCCGCATGTTTCCGGATATCTGTA CCTCACACCAGAGACCCTTTTTTAGAGAAAATCAACAGATCACCGTCTAAGCCTCAGTCCGGGCACCCCA CCTCGCCTGAGCTCAAGCTTCAAGAGTCTGTGACTAAGAGAATTCCGAAAGGATGTGGAGCCCTCTGACT GGGGTGGGCGGGTGTCCTCCAAGGGGCCTCCGGAAGCCCACAGAGGGATGCGCTCCTGCTCAGGCAGGTG TCAGAAGCTTGCAGGGGCTGTGGCCGCAACCTGTGATTAAAGCATTCCTTTCCTGCGTTTCCCCCTTCAC CACTAATGGCTGGCCTTTCTGTGTGCTGAGGTCTTTCGACAGTTCAAATCATCTGGTGGCAGCAGACTCG CCTTTGCCCTTCTGCGGCCGAGGGCGGAGATTTATGACTTTCTCTGCTTGGTTGGAGAAGAAGAATCTTT ACTATTCAGCTTCTTTTCTTTTTGGCCAGAACTCTGAAAAAAAAAAAAACTCTTTTTAAGACAATATTTG TATTCTCACAGGCTCAGCTGTCAATCACTTGAGACCTTCCCTGTAAAGTGGGGCAGATTTTAAATATGGG TGTAGATACTGCTTGCAGCCTTCGCAGGAATTTTGGTTGTGGTTCATTGATTCACACAGACTCTGTGTCA GCTGACAGGGCTGTGTGGGGCATCAAAGGAGGACCAGGCACTGTGGAGAAGACCCATTCACTGGCATCTC ACCCTTCCTTGTCCAGCTCCATACCCAGTCCTAAGACCCAGTGAAAAGCCACGTCCAAACTGTGCTCTGG GCTCATCAGTGCCCACCCACGTACCAGGGAAAGGCACACACCCTACCCAGTGGGCACAGAGCGGAATGTC CCCCTACCGCACCATTTGCGCCCCCAATCTGGCTGTCCAACCTAGTTTGTAAGTAATCTAAATCAGTGAC TATAGCCCCGCCTAAGGGACACTTCCCGGAGGAGGGAGCCGCTGAAATGGAGTTAGTTTGAGGGTCAGTA CACAACAGGGGCAGAAAGCCAAGCAGATGTGGGGGCAGGGAGAGTCATCATCTGCTTTTGTCTGAGAGAA GGAGAGCTTCTCCGTTTGTTCAACTTTGTAACAAGCTGGGTTACATGCTCCACGCAGCTAGAGAAGCCTA GGTGCTCTGCATTCCCTGGGGAACTGCAGGAAAGCCTTACCTGCTGACTGTTGCTCTGGGGAAAAGCCTG AGGGTCCAGAGCAGCTACAAGCTACAGGCCATACCTTACAACCTGAAAAGCTAAGGACCACGGTGACCTT CCCGGCTACTGTGTGAAGGTGCTGGGTGGGGCCTGCTCAACAGACAGGGTCGACAGAGTGTGTGATACAT GCAAACAGAATCCTTGGAGTGTGTGATACATGCAAACAGAATCCTGGGCCCCTGCTTCTCCCCCTCAGTC AAAGCAGGAGTGTCCCTTCCGAAGCCAGGACAACCTGTTCACAAGGCCCCTTGTCACATGTCACCTTCCA CCTGCCTCAAGGAGTGCTAGTGTCCAAATATTTATTTTTGTATTCTCTTAAGAAGTATTGATTTCATCCT TTATTAAAAAAAGTTGCTCTTTCACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_008320
• Insert Size: 1275 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: BC005450, AAH05450
• RefSeq Size: 2878 bp
• RefSeq ORF: 1275 bp
• Locus ID: 15900
• UniProt ID: P23611
• Cytogenetics: 8 70.05 cM
• Summary: The protein encoded by this gene is a transcription factor that belongs to the interferon regulatory factor family. Proteins belonging to this family have a DNA binding domain at the amino terminus that contains five well-conserved tryptophan-rich repeats. This domain recognizes DNA sequences similar to the interferon-stimulated response element. The protein encoded by this gene promotes or suppresses lineage-specific genes to regulate the differentation of lymphoid and myeloid lineage cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]; Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.