Stambp (NM_024239) Mouse Untagged Clone
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
|---|---|
| Target Symbol | Stambp |
| Synonyms | 5330424L14Rik; 5730422L11Rik; Amsh; AW107289; mKIAA4198 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | RsrII-NotI | |
| ACCN | NM_024239 |
| Insert Size | 1275 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | BC003497, AAH03497 |
| RefSeq Size | 2122 bp |
| RefSeq ORF | 1275 bp |
| Locus ID | 70527 |
| UniProt ID | Q9CQ26 |
| Cytogenetics | 6 C3 |
| Summary | Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7 (By similarity). Involved in the ubiquitin-dependent sorting and trafficking of receptors from endosomes to lysosome. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization. Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways (By similarity).UniProtKB/Swiss-Prot Function Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All four variants encode the same protein. |
Reviews
Documents
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Resources
"NM_024239" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MG206746 | Stambp (tGFP-tagged) - Mouse Stam binding protein (Stambp) | 10 ug |
$657.00
|
|
| MR206746 | Stambp (Myc-DDK-tagged) - Mouse STAM binding protein (Stambp) | 10 ug |
$289.00
$457.00
|
|
| MR206746L3 | Lenti ORF clone of Stambp (Myc-DDK-tagged) - Mouse STAM binding protein (Stambp) | 10 ug |
$757.00
|
|
| MR206746L4 | Lenti ORF clone of Stambp (mGFP-tagged) - Mouse STAM binding protein (Stambp) | 10 ug |
$757.00
|
|
Citations
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