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BAX Rabbit Polyclonal Antibody

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SKU
TA890001S
Rabbit polyclonal BAX Antibody
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $188.00
In Stock*
Bulk/Customize

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View other "BAX or NM_138761" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB 1:2000, IHC 1:150
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide conjugated to KLH derived from within residues 100-170 of Human BAX.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 21 kDa
Gene Name BCL2 associated X protein
Database Link
Background The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. provided by RefSeq, Jul 2008
Synonyms BCL2L4
Reference Data
Protein Categories Cancer: Gastrointestinal, Intracellular Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Huntington's disease, Neurotrophin signaling pathway, p53 signaling pathway, Pathways in cancer, Prion diseases
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Documents
Resources
Other antibodies (1)
SKU Description Size Price
TA890001 Rabbit polyclonal BAX Antibody 100 ul
$407.00

file-alt Citations

Nobiletin is capable of regulating certain anti-cancer pathways in a colon cancer cell line
Kisacam
Naunyn Schmiedebergs Arch Pharmacol (2022)
Cited by 12
AI Summary: In this study, OriGene products—specifically anti-Akt (TA311645), anti-EIF4EBP1 (TA321620), anti-Bax (TA890001S), anti-MMP-7 (TA339253), and anti-HO-1 (TA348005) rabbit polyclonal antibodies—were used to measure protein levels and assess how nobiletin regulates anti-cancer pathways in colon cancer cells.
Snippet: odies were purchased from Santa Cruz Biotechnology (CA, USA). Anti-Akt (TA311645), anti-EIF4EBP1 (TA321620), anti-Bax (TA890001S), anti-MMP-7 (TA339253), and anti-HO-1 (TA348005) rabbit policlonal antibodies were obtained from Origene, (Herford, Germany)
CXCL3 overexpression promotes the tumorigenic potential of uterine cervical cancer cells via the MAPK/ERK pathway
Qi, Li, Man et al
J. Cell. Physiol. (2019)
AI Summary: OriGene contributed to this study by providing the rabbit anti-BAX antibody, which was used to assess BAX protein expression in experiments investigating the role of CXCL3 in uterine cervical cancer cells.
Snippet: 2 (1:1,000 dilution;ImmunoWay Biotechnology Company), a rabbit antibody against p‐ERK1/2 (1:1,000 dilution;ImmunoWay Biotechnology Company), a rabbit antibody against Bcl‐2 (1:500 dilution;Santa Cruz), a rabbit antibody against BAX (1:1,000;OriGene, Beijing
WB
High C-X-C motif chemokine 5 expression is associated with malignant phenotypes of prostate cancer cells via autocrine and paracrine pathways
Qi, Zhao, Li et al
Int. J. Oncol. (2018) 53 (1), 358-370 DOI: 10.3892/ijo.2018.4388
AI Summary: In this study, OriGene products—including the anti-NDRG3 antibody (cat. no. TA890001) and the anti-β-actin antibody (cat. no. TA811000)—were used for protein detection in western blot analyses to assess gene expression changes associated with CXCL5 in prostate cancer cells.
Snippet: no. TA890001;OriGene Technologies, Inc., Beijing, China), goat polyclonal anti-NDRG3 (1:200;cat. no no. sc-7148;Santa Cruz Biotechnology, Inc.), and mouse monoclonal anti-β-actin (1:1,000;cat. no. TA811000;OriGene Technologies, Inc.)
Showing 1-3 of 3 papers.
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