HDAC2 Rabbit Polyclonal Antibody

SKU
TA590734
Rabbit Polyclonal HDAC2 Antibody
$482.00
In Stock*
Specifications
Product Data
Application ELISA, IHC, WB
Recommended Dilution WB 1:5000~20000, IHC 1:150,ELISA 1:100-1:2000
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen DNA immunization. This antibody is specific for the C Terminus Region of the target protein.
Buffer 20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Concentration 0.66934 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name histone deacetylase 2
Database Link
Background Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly conserved from yeast to human.
Synonyms HD2; RPD3; YAF1
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
Reference Data
Protein Families Druggable Genome, Stem cell - Pluripotency, Transcription Factors
Protein Pathways Cell cycle, Chronic myeloid leukemia, Huntington's disease, Notch signaling pathway, Pathways in cancer
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Citations

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