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SAMHD1 Mouse Monoclonal Antibody [Clone ID: OTI3F5]

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SKU
TA502024S
SAMHD1 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5)
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $200.00
In Stock*
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View other "SAMHD1 or NM_015474" antibodies

Specifications
Specifications
Product Data
Clone Name OTI3F5
Application FC, IF, IHC, WB
Recommended Dilution WB 1:200~500, IHC 1:150, IF 1:100, FLOW 1:100
Reactivity Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Full length human recombinant protein of human SAMHD1(NP_056289) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 72 kDa
Gene Name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Database Link
Synonyms CHBL2; DCIP; HDDC1; MOP-5; SBBI88
Reference Data
Protein Categories Immune system diseases, Intracellular Proteins
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Other "OTI3F5" antibodies (4)
SKU Description Size Price
CF502024 Carrier-free (BSA/glycerol-free) SAMHD1 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5) 100 ug
$620.00
TA502024 SAMHD1 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5) 100 ul
$447.00
TA502024AM SAMHD1 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5), Biotinylated 100 ul
$509.00
TA502024BM SAMHD1 mouse monoclonal antibody, clone OTI3F5 (formerly 3F5), HRP conjugated 100 ul
$509.00

file-alt Citations

Large-scale drug sensitivity, gene dependency, and proteogenomic analyses of telomere maintenance mechanisms in cancer cells
Wu, Cai, Cross et al
Nat Commun (2025) 16 (1), 11337 DOI: 10.1038/s41467-025-67190-w
Cited by 6
AI Summary: In this study, OriGene’s anti-SAMHD1 antibody (Cat# TA502024) was used for protein detection, contributing to the analysis of telomere maintenance mechanisms in cancer cells.
Snippet: analyzer (LAS-4000, Fujifilm). Primary antibodies: anti-ATRX at 1:400 dilution (Cat#HPA064684 Sigma), anti-DAXX at 1:750 dilution (Cat#HPA008736 Sigma), anti-SAMHD1 at 1:500 dilution (Cat# TA502024, OriGene Technologies Inc.) and anti-Actin at 1:500 dilution (Cat#A2066 Sigma). Secondary antibodies: Goat Anti-Rabbit Immunoglobulins/HRP (1:5000) (Cat# P0448 Agilent) and Goat Anti-Mouse Immunoglobul
FigureFigureFigure
SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
Kapoor-Vazirani, Rath, Liu et al
Nat Commun (2022) 13 (1), 6707 DOI: 10.1038/s41467-022-34578-x
Cited by 28
AI Summary: In this study, OriGene products—including the SAMHD1 Myc-DDK tagged cDNA (RC200807) and SIRT1 Myc-DDK tagged cDNA (RC208447)—were used to express and analyze the roles of SAMHD1 and SIRT1 in DNA double-strand break repair mechanisms.
Snippet: ing to nucleic acids and localization to DNA damage sites are unclear. Sirtuins are NAD+ dependent deacetylases, which regulate multiple biological processes, including genome maintenance, aging, tumorigenesis, and metabolism73–80. There are 7 mammalian homologs of yeast Sir2 that exhibit distinct subcellular localization, with SIRT1, SIRT6, and SIRT7 localized to the nucleus, SIRT2 residing mo
FigureFigureFigure
Rapid, efficient and activation-neutral gene editing of polyclonal primary human resting CD4+ T cells allows complex functional analyses
Albanese, Ruhle, Mittermaier et al
Nat Methods (2021) 19 (1), 81-89 DOI: 10.1038/s41592-021-01328-8
Cited by 42
AI Summary: In this study, the OriGene anti-SAMHD1 antibody (mouse, clone OTI3F5, cat. no. TA502024) was used to detect SAMHD1 protein levels, enabling the functional analysis of gene-edited resting CD4+ T cells.
Snippet: …no. 14326S) 1:1,000 dilution, anti-SAMHD1 (mouse, clone OTI3F5, Origene, cat. … TA502024) 1:250 dilution and anti-GFP (rabbit polyclonal, Chromoteck, PABG1-20) 1:1,000 dilution. …no. 14326S) 1:1,000 dilution, anti-SAMHD1 (mouse, clone OTI3F5, Origene, cat. … TA502024) 1:250 dilution and anti-GFP (rabbit polyclonal, Chromoteck, PABG1-20) 1:1,000 dilution
WB
Specific Deubiquitinating Enzymes Promote Host Restriction Factors Against HIV/SIV Viruses
Gao, Rui, Li et al
Front Immunol (2021) 12, 740713 DOI: 10.3389/fimmu.2021.740713
Cited by 10
AI Summary: OriGene products, specifically the USP8 (RC217863) and USP21 (RC220833) expression plasmids, were used in this study to ectopically express deubiquitinating enzymes and investigate their roles in inhibiting HIV/SIV viral protein-mediated degradation of host restriction factors.
FigureFigureFigure
SAMHD1 inhibits multiple Enteroviruses by interfering with the interaction between VP1 and VP2 proteins
Zhao, Li, Huan et al
J Virol (2021)
AI Summary: In this study, the anti-SAMHD1 monoclonal antibody from OriGene (catalog no. TA502024) was used to detect and analyze SAMHD1 protein expression, enabling the investigation of its antiviral mechanism against multiple enteroviruses.
Snippet: no. 05-724), anti-tubulin mAb (Abcam, Cambridge, Cambridgeshire, UK, catalog no. 351 ab11323), anti-Flag mAb (Sigma, catalog no. F1804), anti-SAMHD1 mAb (Origene, 352 catalog no. TA502024). For confocal microscopy, goat anti-Mouse IgG (H+L) Highly Cross
WB
TRIM21-mediated proteasomal degradation of SAMHD1 regulates its antiviral activity
Li, Huan, Wang et al
EMBO Rep. (2019) 21 (1), e47528 DOI: 10.15252/embr.201847528
Cited by 76
AI Summary: OriGene products, specifically the anti-BST2 polyclonal antibody (TA310217) and the anti-SAMHD1 monoclonal antibody (TA502024), were used in this study to detect and analyze the expression of BST2 and SAMHD1 proteins, supporting the investigation of TRIM21-mediated regulation of SAMHD1’s antiviral activity.
Snippet: …F1804), anti‐BST2 pAb (OriGene, catalog no. TA310217), anti‐SAMHD1 mAb (OriGene, catalog no. TA502024), anti‐Phospho‐SAMHD1 (Thr592) mAb (Prosci, Poway, catalog no. 8005), anti‐TRIM21 pAb (Proteintech, catalog no. 12108‐1‐AP)
WB
Showing 1-6 of 13 papers.
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