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Amyloid Precursor Protein (APP) Mouse Monoclonal Antibody [Clone ID: OTI2B10]

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SKU
TA500973
APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
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Specifications
Specifications
Product Data
Clone Name OTI2B10
Application IF, WB
Recommended Dilution WB 1:2000, IF 1:50
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human APP (NP_000475) produced in HEK293T cell.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 0.74 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 87.0 kDa
Gene Name amyloid beta precursor protein
Database Link
Background This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
Synonyms AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2
Reference Data
Protein Categories Chemokines, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system: Neurodegenerative diseases, Secreated Proteins
Protein Families Druggable Genome, Transmembrane
Protein Pathways Alzheimer's disease
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Other "OTI2B10" antibodies (4)
SKU Description Size Price
CF500973 Carrier-free (BSA/glycerol-free) APP mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 100 ug
$620.00
TA500973AM APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10), Biotinylated 100 ul
$509.00
TA500973BM APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10), HRP conjugated 100 ul
$509.00
TA500973S APP (Amyloid beta precursor protein) mouse monoclonal antibody, clone OTI2B10 (formerly 2B10) 30 ul
$200.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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