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TrkB (NTRK2) Mouse Monoclonal Antibody [Clone ID: OTI2E1]

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SKU
TA500386S
Anti-NTRK2 (TrkB ) mouse monoclonal antibody, clone OTI2E1 (formerly 2E1)
Size:
30 ul 100 ul
Conjugation:
Unconjugated
  $200.00
In Stock*
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Frequently Bought Together (3)

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TP321794 Recombinant protein of human neurotrophic tyrosine kinase, receptor, type 2 (NTRK2), transcript variant a, 20 µg
20 ug
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View other "TrkB or NM_001007097" antibodies

Specifications
Specifications
Product Data
Clone Name OTI2E1
Application IF, IHC, WB
Recommended Dilution WB 1:1000, IHC 1:150, IF 1:100
Reactivity Human
Antibody Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Full length human recombinant protein of human NTRK2 (NP_001007098) produced in HEK293T cell
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1.17 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 92 kDa
Gene Name neurotrophic receptor tyrosine kinase 2
Database Link
Background This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene
Synonyms GP145-TrkB; trk-B; TRKB
Note WB application: Only overexpression results are guaranteed, not endogenous.
Reference Data
Protein Categories Cancer: Brain and CNS, Enzyme: Kinases, Growth Factors, Intracellular Proteins, Membrane Proteins, Nervous system Diseases
Protein Families Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways MAPK signaling pathway, Neurotrophin signaling pathway
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Other "OTI2E1" antibodies (4)
SKU Description Size Price
CF500386 Carrier-free (BSA/glycerol-free) NTRK2 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1) 100 ug
$620.00
TA500386 Anti-NTRK2 (TrkB ) mouse monoclonal antibody, clone OTI2E1 (formerly 2E1) 100 ul
$447.00
TA500386AM Anti-NTRK2 (TrkB ) mouse monoclonal antibody, clone OTI2E1 (formerly 2E1), Biotinylated 100 ul
$509.00
TA500386BM Anti-NTRK2 (TrkB ) mouse monoclonal antibody, clone OTI2E1 (formerly 2E1), HRP conjugated 100 ul
$509.00

file-alt Citations

Rab8A promotes breast cancer progression by increasing surface expression of Tropomyosin-related kinase B
Liu, Zhang, Gao et al
Cancer Lett (2022) 535, 215629 DOI: 10.1016/j.canlet.2022.215629
Cited by 10
AI Summary: OriGene's TrkB antibody (TA500386) was used in this study to detect and analyze TrkB protein expression, contributing to the investigation of Rab8A's role in breast cancer progression.
Snippet: Antibodies for Rab8A (55296-1-AP, Proteintech Group, Chicago, USA), TrkB (TA500386, OriGene, Wuxi, China) and BDNF (66292-1-ig, Proteintech Group, Chicago, USA) were used in this research. The tissues were photographed and analyzed under a microscope (OPTIKA B-150, ITALY). Barnes method was used for statistical analysis [13]
IP
BDNF/TrkB signaling in pancreatic islet beta cells
Kalwat, Huang, McGlynn et al
bioRxiv (2018)
Snippet: Page 1. BDNF/TrkB signaling in pancreatic islet beta cells 1 BDNF/TrkB signaling in pancreatic islet beta cells Michael A. Kalwat1*, Zhimin Huang1,2#, Kathleen McGlynn1, and Melanie H. Cobb1* Department of 1Phamacology View as HTML;TrkB Mouse 145, 95 Origene TA500386 - 1:100 TrkB Mouse 145, 95 Santa Cruz sc-377218 1:100 Anti-human
WB
Human brain proteins showing neuron-specific interactions with γ-secretase
Inoue, Hur, Kihara et al
FEBS J. (2015)
Cited by 19
AI Summary: In this study, the OriGene antibody TA500386 was used to detect Trk-B protein in neurons, contributing to the analysis of neuron-specific interactions between γ-secretase and associated proteins relevant to Alzheimer’s disease research.
Snippet: (F1805, Sigma);rabbit anti-Trk-B (WH0004915M1, Sigma for HEK-APP cells, TA500386, Origene for neurons);rabbit anti-SLC2A13 (OB1417, DSP for HEK-APP cells;BMP026, MBL for neurons);rabbit anti-GAP43 (OB1415, DSP);rabbit anti-GAP43 (75810, Abcam ... Cite SaveSaving
Showing 1-3 of 3 papers.
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