OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Cytokeratin 8 (KRT8) Mouse Monoclonal Antibody [Clone ID: OTI1B12]

  • Product Brand Image
Be the first to review this product
SKU
TA500021
CK8 (Keratin 8) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12)
Size:
100 ul 30 ul
Formulation:
Standard Carrier-free
Conjugation:
Unconjugated Biotin HRP
  $447.00
In Stock*
Bulk/Customize

Frequently Bought Together (3)

TA811000S beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control 30 ul
$200.00
LY419425 Transient overexpression lysate of keratin 8 (KRT8) (as WB positive control) 100 ug
$436.00
TP309570 Recombinant protein of human keratin 8 (KRT8), 20 µg
20 ug
$867.00

View other "Cytokeratin 8 or NM_002273" antibodies

Specifications
Specifications
Product Data
Clone Name OTI1B12
Application IF, IHC, Simple Western, WB
Recommended Dilution WB 1:2500~5000, IHC 1:50 - 1:150, IF 1:50 - 1:100, Simple Western 1:20-1:50
Simple Western 1:50-1:100
Reactivity Dog, Human, Monkey, Mouse, Rat
Antibody Host Mouse
Isotype IgG2b
Clonality Monoclonal
Immunogen Human recombinant protein fragment corresponding to amino acids 91-381 of human CK8 (NP_002264) produced in E.coli.
Buffer PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide
Concentration 1 mg/ml
Purification Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 53.5 kDa
Gene Name keratin 8
Database Link
Background Keratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Synonyms CARD2; CK-8; CK8; CYK8; K2C8; K8; KO
Reference Data
Protein Categories ADC Targets, Intracellular Proteins
Protein Families Druggable Genome
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other "OTI1B12" antibodies (4)
SKU Description Size Price
CF500021 Carrier-free (BSA/glycerol-free) CK8 mouse monoclonal antibody, clone OTI1B12 (formerly 1B12) 100 ug
$620.00
TA500021AM CK8 mouse monoclonal antibody, clone 1B12, Biotinylated 100 ul
$509.00
TA500021BM CK8 mouse monoclonal antibody, clone 1B12, HRP conjugated 100 ul
$509.00
TA500021S CK8 (Keratin 8) mouse monoclonal antibody, clone OTI1B12 (formerly 1B12) 30 ul
$200.00

file-alt Citations

The Prognostic Value of Cytokeratin and Sal-Like Protein 4 Expression in Hepatocellular Carcinoma and Intra-Hepatic Cholangiocarcinoma in Taiwan
Lai, Cheng, Lee et al
Int J Med Sci (2018) 15 (14), 1746-1756 DOI: 10.7150/ijms.28440
Cited by 10
AI Summary: In this study, OriGene products—including anti-cytokeratin 7, anti-cytokeratin 8, anti-cytokeratin 18, anti-cytokeratin 19, and anti-SALL4 antibodies—were used for immunohistochemical detection of protein expression in liver cancer tissues, enabling the assessment of their prognostic value in hepatocellular carcinoma and intra-hepatic cholangiocarcinoma.
FigureFigureFigure
Stress chaperone mortalin contributes to epithelial-mesenchymal transition and cancer metastasis
Na, Kaul, Ryu et al
Cancer Res. (2016)
AI Summary: OriGene’s Keratin 8 antibody was used in this study to assess changes in epithelial marker expression, helping to demonstrate mortalin’s role in promoting epithelial-mesenchymal transition and cancer cell invasiveness.
Snippet: Cambridge, MA);hnRNP-K, MMP-2, MMP-3 &fibronectin (Santa Cruz Biotechnology, Santa Cruz, CA);Keratin 8 (OriGene Technologies, Rockville, MD);Keratin 14 (Anaspec, San Jose, CA);Keratin 18, myc-tag and β-actin (Cell Signaling Technology), and Alexa Fluor ... Cite SaveSaving
The Prognostic Value of Cytokeratin and Sal-Like Protein 4 Expression in Hepatocellular Carcinoma and Intra-Hepatic Cholangiocarcinoma in Taiwan
Lai, Cheng, Lee et al
Int J Med Sci (2018)
Snippet: … CK8, Mouse monoclonal, TA500021, IgG2b, OriGene, 1:200, ER2 20 min. CK18, Mouse monoclonal, TA500015, IgG1, OriGene, 1:200, ER2 20 min. SALL4, Rabbit monoclonal, EP299, IgG, ZETA, 1;CK19 Mouse monoclonal BA17 IgG1 ZETA 1:100 ER2 20 min CK8 Mouse monoclonal TA500021 IgG2b OriGene 1:200 ER2 20 min CK18 Mouse monoclonal TA500015 IgG1 OriGene 1:200 ER2 20 min SALL4 Rabbit monoclonal EP299 IgG ZETA 1:200 ER2 20 min View as HTML
IHC
Showing 1-3 of 3 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products