MOBK1B (MOB1A) Rabbit Polyclonal Antibody

SKU TA351408

Rabbit Polyclonal Anti-MOB1A Antibody

Product Data

• Application: IHC, WB
• Recommended Dilution: WB: 500-2000; WB positive control: Hela and Jurkat cells, mouse liver tissue, K562 and A375 cells; IHC: 50-200; Positive control: Human liver cancer; Predicted cell location: Cytoplasm and Nucleus
• Reactivity: Human, Mouse, Rat
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human MOB1A
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Predicted Protein Size: 25 kDa
• Gene Name: MOB kinase activator 1A
• Database Link:
  NP_060691
  Q9H8S9
• Background: MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy. Its Drosophila and mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumor suppressor pathway, which plays a critical role in organ size regulation and which has been implicated in cancer development . There are two MOB1 proteins in humans, MOB1α and MOB1β, that are encoded by two different genes but which have greater than 95% amino acid sequence identity.
• Synonyms: C2orf6; MATS1; MOB1; Mob4B; MOBK1B; MOBKL1B

Reference Data

• Protein Families: Druggable Genome