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CAB39 Rabbit Polyclonal Antibody

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SKU
TA351407
Rabbit Polyclonal Anti-CAB39 Antibody
Size:
100 ul
Conjugation:
Unconjugated
  $205.00
In Stock*
Bulk/Customize

Frequently Bought Together (3)

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20 ug
$867.00

View other "CAB39 or NM_016289" antibodies

Specifications
Specifications
Product Data
Application IHC, WB
Recommended Dilution WB: 500-2000
WB positive control: 293T and LoVo cells, human brain malignant glioma tissue
IHC: 50-200
Positive control: Human cervical cancer
Predicted cell location: Cytoplasm and Nucleus
Reactivity Human, Mouse
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide of human CAB39
Buffer pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 40 kDa
Gene Name calcium binding protein 39
Database Link
Background Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
Synonyms CGI-66; MO25
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways mTOR signaling pathway
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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