LLGL2 Rabbit Polyclonal Antibody

SKU TA351357

Rabbit Polyclonal Anti-LLGL2 rabbit polyclonal antibody

Product Data

• Application: IHC
• Recommended Dilution: IHC: 25-100; Positive control: Human thyroid cancer; Predicted cell location: Cytoplasm
• Reactivity: Human, Mouse
• Antibody Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of human LLGL2
• Buffer: pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Shipping: Blue Ice
• Gene Name: LLGL2, scribble cell polarity complex component
• Database Link:
  NP_004515
  Q6P1M3
• Background: The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Synonyms: HGL; Hugl-2; LGL2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Tight junction