H2AW Rabbit Polyclonal Antibody

SKU
TA347207
Rabbit Polyclonal H2A pan Antibody
  $645.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application ELISA, WB
Recommended Dilution ChIP (1-2 µg/ChIP); ELISA (1:100-1:1,000); Western blotting (1:2,000)
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen The immunogen for anti-H2A pan antibody: histone H2A using 2 KLH-conjugated synthetic peptides containing a sequence from the central and the C-terminal part of the protein.
Concentration lot specific
Purification Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name histone cluster 3, H2a
Database Link
Background Histones are the main constituents of the protein part of chromosomes of eukaryotic cells. They are rich in the amino acids arginine and lysine and have been greatly conserved during evolution. Histones pack the DNA into tight masses of chromatin. Two core histones of each class H2A, H2B, H3 and H4 assemble and are wrapped by 146 base pairs of DNA to form one octameric nucleosome. Histones play a central role in the regulation of transcription, DNA repair, DNA replication and chromosomal stability. These different functions are established via a complex set of post-translational modifications which either directly or indirectly alter chromatin structure and DNA accessibility to facilitate transcriptional activation or repression or other nuclear processes.
Synonyms MGC3165
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways Systemic lupus erythematosus
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