APRT Rabbit Polyclonal Antibody

SKU
TA324753
APRT Antibody (N-term)
  $645.00
5 Days*
Bulk/Customize
Specifications
Specifications
Product Data
Application FC, IF, IHC, WB
Recommended Dilution WB:1/1000, IHC-P:1/50-200, IF:1/10-50, FC:1/10-50
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT.
Specificity This APRT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human APRT.
Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Concentration lot specific
Purification Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Shelf life: one year from despatch.
Shipping Blue Ice
Predicted Protein Size 19.6 kDa
Gene Name adenine phosphoribosyltransferase
Database Link
Background A conserved feature of APRT is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis.
Synonyms AMP; APRTD
Reference Data
Protein Families Druggable Genome
Protein Pathways Metabolic pathways, Purine metabolism
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