Epac2 (RAPGEF4) Rabbit Polyclonal Antibody

SKU
TA319831
Rabbit Polyclonal EPAC2 Antibody
In Control Promo
  $640.00
2 Weeks*
Bulk/Customize
Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution WB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 20 ug/mL
Reactivity Human, Mouse, Rat
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen EPAC2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human EPAC2.
Buffer EPAC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration 1 mg/ml
Purification EPAC2 Antibody is affinity chromatography purified via peptide column.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Gene Name Rap guanine nucleotide exchange factor 4
Database Link
Background EPAC2 Antibody: EPAC2, also known as Rap guanine nuclear exchange factor 4 and cAMPGEF-II, is belongs to a family of cyclic adenosine monophosphate (cAMP) binding proteins with guanine nucleotide exchange factor. Like the related protein EPAC1, EPAC2 signaling plays a role in numerous cellular processes such as integrin-mediated cell adhesion, muscle contraction, learning and memory, cell proliferation, and inflammation. Recent evidence suggests that EPAC2 induces synapse remodeling and depression, with mutations in its gene being found in patients with autism.
Synonyms CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496
Reference Data
Protein Categories Intracellular Proteins
Protein Pathways Leukocyte transendothelial migration
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