ULK1 Rabbit Polyclonal Antibody
Rabbit Polyclonal ULK1 Antibody
Product Datasheet for 'TA319746'
|Applications||IF, IHC, WB|
|Recommend Dilution||WB: 1 ug/mL|
|Reactivity||Human, Mouse, Rat|
|Immunogen||ULK1 antibody was raised against a 16 amino acid peptide near the center of human ULK1 .|
|Formulation||ULK1 Antibody is supplied in PBS containing 0.02% sodium azide.|
|Purification||ULK1 Antibody is affinity chromatography purified via peptide column.|
|Predicted Protein Size||Predicted: 116 kDa; Observed: 105 kDa|
|Gene Name||unc-51 like autophagy activating kinase 1|
|Background||ULK1 Antibody: ULK1, also known as ATG1, is a key serine/threonine protein kinase probably acting at the most upstream step of autophagosome formation. Knockout of ULK1 results in a severe defect in the autophagy pathway. ULK1 is highly conserved among eukaryotes, and are the Unc-51-like kinases, ULK1 and ULK2 in mammals. ULK1 is ubiquitously expressed and involved in autophagy in response to starvation. It is the target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13. ULK1 also plays a role early in neuronal differentiation.|
|Synonyms||ATG1; ATG1A; hATG1; UNC51; Unc51.1|
|Protein Families||Druggable Genome, Protein Kinase|
|Protein Pathways||mTOR signaling pathway, Regulation of autophagy|
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.