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BCCIP Rabbit Polyclonal Antibody

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SKU
TA308557
Rabbit polyclonal antibody to TOK-1 alpha (BRCA2 and CDKN1A interacting protein)
Size:
100 ul
Conjugation:
Unconjugated
  $665.00
5 Days*
Bulk/Customize

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View other "BCCIP or NM_016567" antibodies

Specifications
Specifications
Product Data
Application IF, IHC, WB
Recommended Dilution ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Reactivity Human
Antibody Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region within amino acids 181 and 273 of BCCIP (Uniprot ID#Q9P287)
Buffer 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration lot specific
Purification Purified by antigen-affinity chromatography.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Shipping Blue Ice
Predicted Protein Size 36 kDa
Gene Name BRCA2 and CDKN1A interacting protein
Database Link
Background This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. provided by RefSeq
Synonyms TOK-1; TOK1
Reference Data
Protein Categories Intracellular Proteins
Protein Families Druggable Genome, Stem cell - Pluripotency
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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