MX1 Rabbit Polyclonal Antibody
SKU
TA308496
Rabbit Polyclonal antibody to MX1 (myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse))
$665.00
In Stock*
Specifications
| Product Data | |
| Application | IF, IHC, WB |
|---|---|
| Recommended Dilution | ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000 |
| Reactivity | Human |
| Antibody Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 194 and 475 of MX1 (Uniprot ID#P20591) |
| Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Shipping | Blue Ice |
| Predicted Protein Size | 76 kDa |
| Gene Name | MX dynamin like GTPase 1 |
| Database Link | |
| Background | In mouse, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin family and the family of large GTPases. Two transcript variants encoding the same protein have been found for this gene. provided by RefSeq |
| Synonyms | IFI-78K; IFI78; MX; MxA |
| Reference Data | |
| Protein Categories | Intracellular Proteins |
| Protein Families | Druggable Genome |
Reviews
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Citations
Antibody-drug conjugates harboring a kinesin spindle protein inhibitor with immunostimulatory properties
Sommer, Berndt, Lerchen et al
Oncoimmunology (2022) 11 (1), 2037216 DOI: 10.1080/2162402X.2022.2037216
Sommer, Berndt, Lerchen et al
Oncoimmunology (2022) 11 (1), 2037216 DOI: 10.1080/2162402X.2022.2037216
AI Summary: OriGene’s MX1-specific antibody (TA308496) was used in this study to detect MX1 expression by immunofluorescence, helping to assess the type-I interferon response in cancer cells treated with antibody-drug conjugates.
Snippet: … MX1 expression in NCI-H929 and HCC70 in response to type-I interferon was detected by immunofluorescence utilizing an MX1-specific antibody (Origene;TA308496) and automated image analysis. For the detection of ATP containing vesicles, the cells were labeled after 4, 8, 16, or 32 hours of incubation with quinacrine. In short, cells were l;- MX1 expression in NCI-H929 and HCC70 in response to type-I interferon was detected by immunofluorescence utilizing an MX1-specific antibody (Origene;TA308496)
HeLa cell response proteome alterations induced by mammalian reovirus T3D infection
Coombs
Virol J (2013) 10, 202 DOI: 10.1186/1743-422X-10-202
Coombs
Virol J (2013) 10, 202 DOI: 10.1186/1743-422X-10-202
AI Summary: In this study, OriGene's anti-β-actin antibody (TA-09) was used as a loading control in Western blot experiments to validate proteomic findings related to HeLa cell protein alterations following reovirus T3D infection.
Showing 1-2 of 2 papers.
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