CTIP2 (BCL11B) Human shRNA Plasmid Kit (Locus ID 64919)
SKU
TL306424
BCL11B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
$1,013.00
In Stock*
Specifications
| Product Data | |
| Locus ID | 64919 |
|---|---|
| Synonyms | ATL1; ATL1-alpha; ATL1-beta; ATL1-delta; ATL1-gamma; CTIP-2; CTIP2; hRIT1-alpha; IDDFSTA; IMD49; RIT1; ZNF856B |
| Vector | pGFP-C-shLenti |
| E. coli Selection | Chloramphenicol (34 ug/ml) |
| Mammalian Cell Selection | Puromycin |
| Format | Lentiviral plasmids |
| Components | BCL11B - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 64919). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free. |
| RefSeq | NM_001282237, NM_001282238, NM_022898, NM_138576, NM_138576.1, NM_138576.2, NM_138576.3, NM_022898.1, NM_022898.2, NM_001282238.1, NM_001282237.1, BC156139, NM_138576.4, NM_001282237.2, NM_022898.3, NM_001282238.2 |
| UniProt ID | Q9C0K0 |
| Summary | This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Aug 2013 |
| shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
| Storage | Store at -20°C |
| Shipping | Ambient |
Reviews
Documents
Resources
Citations
Directly reprogrammed NK cells driven by BCL11B depletion enhance targeted immunotherapy against pancreatic ductal adenocarcinoma
Kim, Kim, Lee et al
J Hematol Oncol (2025) 18 (1), 100 DOI: 10.1186/s13045-025-01730-1
Kim, Kim, Lee et al
J Hematol Oncol (2025) 18 (1), 100 DOI: 10.1186/s13045-025-01730-1
Cited by 3
AI Summary: OriGene’s BCL11B Human shRNA Plasmid Kit (#TL306424) was used to generate lentiviral shRNAs for targeted knockdown of BCL11B, enabling the direct reprogramming of NK cells studied in this paper.
Snippet: hnology). Cells were maintained in 1 F-RM II for an additional 12 days. Lentiviral plasmids encoding short hairpin RNAs (shRNAs) targeting human BCL11B or a non-targeting control were obtained from Origene (BCL11B Human shRNA Plasmid Kit, #TL306424). The target sequences used for BCL11B knockdown were as follows: shBCL11B-#1 (5′-CAG ATC GGC AAG GAG GTG TA-3′), shBCL11B-#2 (5′-CCT AAC CTG T
Showing 1-1 of 1 papers.
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