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Nucleostemin (GNL3) Human shRNA Plasmid Kit (Locus ID 26354)

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SKU
TL304295
GNL3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector, 5µg of each construct provided
  $1,013.00
2 Weeks*

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Specifications
Specifications
Product Data
Locus ID 26354
Synonyms C77032; E2IG3; NNP47; NS
Vector pGFP-C-shLenti
E. coli Selection Chloramphenicol (34 ug/ml)
Mammalian Cell Selection Puromycin
Format Lentiviral plasmids
Components GNL3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector(Gene ID = 26354). 5µg purified plasmid DNA per construct
29-mer scrambled shRNA cassette in pGFP-C-shLenti Vector, TR30021, included for free.
RefSeq NM_014366, NM_206825, NM_206826, NM_014366.1, NM_014366.2, NM_014366.3, NM_014366.4, NM_206825.1, NM_206826.1, BC001024, BC001024.2
UniProt ID Q9BVP2
Summary The protein encoded by this gene may interact with p53 and may be involved in tumorigenesis. The encoded protein also appears to be important for stem cell proliferation. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene. provided by RefSeq, Nov 2010
shRNA Design These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service.
Storage Store at -20°C
Shipping Ambient
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Documents
Resources

file-alt Citations

GNL3 Orchestrates AR Transcriptional Programs to Drive Castration-Resistant Prostate Cancer and Immune Evasion
Zhang, Cheong, Narwade et al
Adv Sci (Weinh) (2026)
Cited by 1
AI Summary: OriGene’s shGNL3 plasmid (TL304295) was used to knock down GNL3 expression in 293T cells, enabling the study of GNL3’s role in androgen receptor signaling and immune evasion in castration-resistant prostate cancer.
Snippet: 293T cells (gifted kindly from Professor Chuxia Deng, University of Macau) were cultured for a package of lentivirus using corresponding plasmids such as psPAX2, pMD2.G, and shGNL3 (OriGene, TL304295) plasmids
Showing 1-1 of 1 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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