beta Actin (ACTB) (NM_001101) Human Untagged Clone
$457.00
In Stock*
Specifications
| Product Data | |
| Type | Human Untagged Clone |
|---|---|
| Target Symbol | beta Actin |
| Synonyms | BRWS1; PS1TP5BP1 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Restriction Sites | Please inquire | |
| ACCN | NM_001101 |
| Insert Size | 1128 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001101.2, NP_001092.1 |
| RefSeq Size | 1793 bp |
| RefSeq ORF | 1128 bp |
| Locus ID | 60 |
| UniProt ID | P60709 |
| Cytogenetics | 7p22.1 |
| Domains | ACTIN |
| Protein Families | ES Cell Differentiation/IPS |
| Protein Pathways | Adherens junction, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Regulation of actin cytoskeleton, Tight junction, Vibrio cholerae infection, Viral myocarditis |
| Summary | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. provided by RefSeq, Aug 2017 |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001101" in other vectors (6)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| RC203643 | ACTB (Myc-DDK-tagged)-Human actin, beta (ACTB) | 10 ug |
$457.00
|
|
| RC203643L1 | Lenti ORF clone of Human actin, beta (ACTB), Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC203643L2 | Lenti ORF clone of Human actin, beta (ACTB), mGFP tagged | 10 ug |
$757.00
|
|
| RC203643L3 | Lenti ORF clone of Human actin, beta (ACTB), Myc-DDK-tagged | 10 ug |
$757.00
|
|
| RC203643L4 | Lenti ORF clone of Human actin, beta (ACTB), mGFP tagged | 10 ug |
$757.00
|
|
| RG203643 | ACTB (tGFP-tagged) - Human actin, beta (ACTB) | 10 ug |
$489.00
$657.00
|
|
Citations
Congenital Kir6.2 deficiency, but not acute KATP channel blockade, attenuates apomorphine-induced locomotor activity in mice
Mochida-Saito, Umeda, Okada et al
Pharmacol Biochem Behav (2026) 265, 174209 DOI: 10.1016/j.pbb.2026.174209
Mochida-Saito, Umeda, Okada et al
Pharmacol Biochem Behav (2026) 265, 174209 DOI: 10.1016/j.pbb.2026.174209
AI Summary: OriGene’s pCMV6-AC beta actin plasmid (SC319328) was used in this study as a recombinant DNA tool, likely serving as a control or reference in gene expression experiments related to dopamine-related protein analysis.
Snippet: Recombinant DNA pCMV6-AC beta actin plasmid Origene SC319328 Software and algorithms xPONENT 4.2 software Luminex MAGPIX https://www.rndsystems.com/products/luminex-magpix-instrument-with-xponent-43_magpix-xpon42
Distinct in vivo dynamics of donor-derived stem cell memory CAR T cells post-allogeneic HSCT relapse
Gattinoni, Inchingolo, Harrer et al
Cell (2026)
Gattinoni, Inchingolo, Harrer et al
Cell (2026)
Cited by 12
AI Summary: OriGene's pCMV6-AC beta actin plasmid (SC319328) was used in this study to support recombinant DNA experiments related to the analysis of donor-derived CAR T cell dynamics after allogeneic HSCT relapse.
Snippet: Recombinant DNA pCMV6-AC beta actin plasmid Origene SC319328 Software and algorithms xPONENT 4.2 software Luminex MAGPIX https://www.rndsystems.com/products/luminex-magpix-instrument-with-xponent-43_magpix-xpon42
Corticosteroids ameliorate CAR T-cell-induced cytokine-release syndrome without inhibiting multiple myeloma treatment
Amatya, Weissler, Lam et al
J Immunother Cancer (2026) 14 (2) DOI: 10.1136/jitc-2025-012437
Amatya, Weissler, Lam et al
J Immunother Cancer (2026) 14 (2) DOI: 10.1136/jitc-2025-012437
AI Summary: OriGene's ACTB plasmid (part# SC319328) was used as a standard in quantitative PCR assays to normalize human β-actin levels, enabling accurate measurement of CAR T-cell abundance in the study.
Snippet: …For the actin qPCR, serial dilutions of an actin plasmid (Origene part# SC319328 ACTB NM_001101) were amplified in duplicate with a p;- For the actin qPCR, serial dilutions of an actin plasmid (Origene part# SC319328 ACTB NM_001101) were amplified in duplicate with a primer and probe set (Bio-Rad
E2F1-activated SPIN1 promotes tumor growth via a MDM2-p21-E2F1 feedback loop in gastric cancer
Lv, Ma, Chen et al
Mol Oncol (2020) 14 (10), 2629-2645 DOI: 10.1002/1878-0261.12778
Lv, Ma, Chen et al
Mol Oncol (2020) 14 (10), 2629-2645 DOI: 10.1002/1878-0261.12778
Cited by 38
AI Summary: In this study, OriGene products including the SPIN1 overexpression plasmid (RC210307) and SPIN1 shRNA (TL313960) were used to manipulate SPIN1 expression in gastric cancer cells, enabling the authors to investigate the role of SPIN1 in tumor growth and its regulation via the MDM2-p21-E2F1 feedback loop.
Overexpression miR-486-3p Promoted by Allicin Enhances Temozolomide Sensitivity in Glioblastoma Via Targeting MGMT
Wu, Li, Zhang et al
Neuromolecular Med. (2020)
Wu, Li, Zhang et al
Neuromolecular Med. (2020)
Cited by 37
AI Summary: OriGene’s DAB Detection System was used in this study to visualize protein bands during Western blot analysis, supporting the investigation of molecular mechanisms underlying Allicin-enhanced temozolomide sensitivity in glioblastoma.
Snippet: Following washing, the protein bands were detected with ECL substrates or DAB Detection System (OriGene Technologies, Inc., Beijing, China). β-actin (sc-47778, Santa Cruz, USA) was used as a loading control, and all experiments were repeated three times;- Following washing, the protein bands were detected with ECL substrates or DAB Detection System (OriGene Technologies, Inc., Beijing, China). β-actin (sc-47778, Santa Cruz, USA) was used as a loading control, and all experiments were repeated three times
Dual actions of norathyriol as a new candidate hypouricaemic agent: uricosuric effects and xanthine oxidase inhibition
Lin, Tu, Niu et al
Eur. J. Pharmacol. (2019) 853, 371-380 DOI: 10.1016/j.ejphar.2019.04.034
Lin, Tu, Niu et al
Eur. J. Pharmacol. (2019) 853, 371-380 DOI: 10.1016/j.ejphar.2019.04.034
AI Summary: OriGene products, specifically antibodies against OAT1, OAT3, MRP4, and β-actin, were used in this study to detect and quantify the expression of key renal transporters and control proteins, thereby supporting the investigation of norathyriol’s mechanisms in lowering uric acid levels.
Snippet: organic anion transporter 1 (OAT1) (1:2000, Origene Technologies, Rockville, USA), organic anion transporter 3 (OAT3) (1:1000, Origene Technologies, Rockville, USA), multidrug resistance protein 4 (MRP4) (1:1000, Origene Technologies, Rockville, USA), breast cancer resistance protein (BCRP/ABCG2) (1:800, Proteintech Group, Wuhan, China), Na, K-ATPase (1:1000, Cell Signaling Technology, Danvers, USA), β-actin (1:2000, Origene Technologies
Showing 1-6 of 16 papers.
Powered by BizGenius
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen
complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.
Related Products
- Price:
- Actual Price:
Welcome to OriGene AI!
I'm your AI-powered guide to everything OriGene.
Ask me anything:
- Product specs
- Ordering help
- Technical questions
- How to find exactly what your experiment needs
Prefer a live agent? Connect with us by clicking the green chat icon, as seen in the image below or email our team at custsupport@origene.com.
