Eda2r (NM_001161432) Mouse Tagged ORF Clone
- TrueORF®
SKU
MG222258
Eda2r (tGFP-tagged) - Mouse ectodysplasin A2 receptor (Eda2r) transcript variant 1, (10ug)
$650.00
In Stock*
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
|---|---|
| Target Symbol | Eda2r |
| Synonyms | 9430060M22Rik; TNFRSF27; Xedar |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data | |
| Chromatograms |
Chromatograms
 Sequencher program is needed, download here |
| Restriction Sites |
SgfI-MluI Cloning Scheme for this gene
|
Plasmid Map
|
| ACCN | NM_001161432 |
| ORF Size | 891 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution Method | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Shipping | Ambient |
| Reference Data | |
| RefSeq | NM_001161432.1, NP_001154904.1 |
| RefSeq Size | 4798 bp |
| RefSeq ORF | 894 bp |
| Locus ID | 245527 |
| UniProt ID | Q8BX35 |
| Cytogenetics | X C3 |
| Summary | Receptor for EDA isoform A2, but not for EDA isoform A1. Mediates the activation of the NF-kappa-B and JNK pathways. Activation seems to be mediated by binding to TRAF3 and TRAF6 (By similarity).UniProtKB/Swiss-Prot Function |
Reviews
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
"NM_001161432" in other vectors (4)
| SKU | Description | Size | Price | |
|---|---|---|---|---|
| MC213218 | Eda2r (untagged) - Mouse ectodysplasin A2 receptor (Eda2r), transcript variant 1, (10ug) | 10 ug |
$480.00
|
|
| MR222258 | Eda2r (Myc-DDK-tagged) - Mouse ectodysplasin A2 receptor (Eda2r), transcript variant 1 | 10 ug |
$450.00
|
|
| MR222258L3 | Lenti ORF clone of Eda2r (Myc-DDK-tagged) - Mouse ectodysplasin A2 receptor (Eda2r), transcript variant 1 | 10 ug |
$750.00
|
|
| MR222258L4 | Lenti ORF clone of Eda2r (mGFP-tagged) - Mouse ectodysplasin A2 receptor (Eda2r), transcript variant 1 | 10 ug |
$750.00
|
|
Citations
Increased ectodysplasin-A2-receptor EDA2R is a ubiquitous hallmark of aging and mediates parainflammatory responses
Barbera, Guarrera, Re Cecconi et al
Nat Commun (2025) 16 (1), 1898 DOI: 10.1038/s41467-025-56918-3
Barbera, Guarrera, Re Cecconi et al
Nat Commun (2025) 16 (1), 1898 DOI: 10.1038/s41467-025-56918-3
Cited by 32
AI Summary: OriGene contributed to this study by providing the EDA2R plasmid and the EDA2R-pCMV6-AC-GFP-expressing plasmid (MG222258), which were used to manipulate EDA2R expression in cell models to investigate its role in aging and parainflammatory responses.
Snippet: Then, 3 μg of plasmid DNA (EDA2R, Origene) was added to the cell suspension and subjected to nucleofection using the Amaxa Nucleofector Device with the A-033;e myoblasts by lipofectamine C2C12 myoblasts were grown in a 6-well plate and transfected with pCMX-GFP plasmid (gifted from Prof. Kakizuka, Japan) or EDA2R-pCMV6-AC-GFP-expressing plasmid (MG222258, Origene) using Lipofectamine 2000 (Life Technologies), according to the manufacturer’s directions. …
Showing 1-1 of 1 papers.
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