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Scrambled shRNA control in pRFP-C-shLenti vector

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SKU
TR30031
29-mer Scrambled shRNA Cassette in p-RFP-C-shLenti Vector, 5 ug
  $670.00
In Stock*
Specifications
Specifications
Product Data
Control Type Negative
Fluorescent Label None
Mammalian Cell Selection Puromycin
Viral Packaging Lentiviral
Features Transfection grade purified shRNA plasmid carrying a 29-mer scrambled sequence cassette. This product is a negative control for OriGene’s gene specific HuSH shRNA lentiviral products.
Download Vector Sequence
Components 1 vial of 5 ug lyophilized 29-mer Scrambled shRNA control in pRFP-C-shLenti Vector
Quality Control This vector was sequence verified and functionally validated.
Storage Store the vector DNA at -20°C.
Stability Vector DNA is stable for at least one year from date of receipt when stored at -20°C.
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Documents
Resources

file-alt Citations

MAGMAS Inhibition Enhances Temozolomide Efficacy in Chemotherapy-Resistant Glioblastoma Models
Lepe, Tran, Lomeli et al
Cancer Res Commun (2026) 6 (6), 1351-1363 DOI: 10.1158/2767-9764.CRC-25-0493
AI Summary: OriGene products TL317164 (shRNA targeting PAM16/MAGMAS) and TR30031 (lentiviral packaging mix) were used to generate viral particles for transducing glioma cells, enabling the study of MAGMAS knockdown and its effect on temozolomide sensitivity in chemotherapy-resistant glioblastoma models.
Snippet: Generated viral particles (OriGene TL317164 and TR30031) were added, and cells were incubated overnight. The following day, the media was removed, cells were washed once with PBS and exchanged with fresh complete media for expansion. Successful transduction was observed by a positive GFP signal
Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
Park, Mossmann, Chen et al
Mol Cell (2022) 82 (22), 4246-4261.e11 DOI: 10.1016/j.molcel.2022.10.027
Cited by 31
AI Summary: In this study, OriGene products—specifically the TEAD2 (Cat# SR307879) and E2A (Cat# SR305024) shRNA lentiviral particles—were used to knock down TEAD2 and E2A expression, enabling the authors to demonstrate that these transcription factors repress acetyl-CoA synthesis and thereby promote tumorigenesis.
Snippet: Transcription factors TEAD2 and E2A globally repress acetyl-CoA synthesis to promote tumorigenesis
Microenvironmental interleukin-6 suppresses toll-like receptor signaling in human leukemia cells through miR-17/19A
Li, Shi, McCaw et al
Blood (2015)
Cited by 46
AI Summary: OriGene’s pGFP-C-shlenti vector was used to clone shRNA targeting STAT3, enabling the researchers to investigate the role of STAT3 in IL6-mediated suppression of TLR signaling in leukemia cells.
Snippet: shRNA-STAT3: An shRNA template was designed and cloned into the BamHI and BsmBI sites of pGFP-C-shlenti (ORIGENE, Rockville, USA). 19 Coding regions used to ... lenti (ORIGENE) with a H1 expression cassette to provide constitutive RNA polymerase ... Cite SaveSaving
Showing 1-3 of 3 papers.
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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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